Organometallic Chemistry

Goals
The course aims to train students on the aspects of frontier applications of organometallic chemistry. Fundamental aspects of organometallic compounds will be described. Application to synthetic organic reactions using these organometallic compounds will be presented.

acquired skills
The course is aimed at the introduction to organometallic chemistry for students confronted with the field for the first time. The material covered is a mixture of indispensable milestones and basic facts and selected examples of the most recent literature. Attempts to systematize organometallic chemistry by relating molecular structures to the number and nature of the valence electrons are presented. Applications of organometallics in organic synthesis as well as industrial processes based on homogeneous catalysis are illustrated.

Course content
This course examines important transformations of organometallic species with an emphasis on basic mechanisms, structure-reactivity relationships, spectroscopic characterization and applications in organic synthesis.
1) Introduction. 2) Energy, polarity, and reactivity of the M-C bond. 3) Main group organometallics: overview of preparation methods. 4) Organometallic chemistry of alkali metals. 5) Organometallic compounds of groups 2 and 12. 6) Organometallic chemistry of boron, aluminium and indium. 7) Organoelement compounds of the carbon group. 8) Organometallic chemistry of copper, silver and gold. 9) Survey of organotransition metal complexes according to ligand. Structure and bonding. Reactivity. Applications in organic chemistry. 9a) -donor ligands: transition metal -alkyls and -aryl compounds. 9b) -donor -donor / -acceptor ligands: olefin and allyl complexes. 9c) -donor / -acceptor ligands: transition metal carbene and carbyne complexes. 10) NMR spectroscopy (1H, 13C, 31P and heteronuclei) applied to the characterization and reactivity studies of organometallic complexes

Suggested prerequisites
Expected to have basic knowledge of organic and inorganic chemistry. The student must also have already acquired the fundamental principles of coordination chemistry.

Reference material
There is no mandatory text: the teaching material will be provided by the teacher in the form of file.pdf downloadable from the network. However, it is recommended that the student could access one or more of the following books:
Crabtree, Robert H. The Organometallic Chemistry of the Transition Metals. 5th ed. New York, NY: John Wiley, 2009.
Elschenbroich, Christoph Organometallics 3rd, fully revised and extended ed. Weinheim, Germany: Wiley-VCH, 2006.
Cotton, F. Albert; Wilkinson, Geoffrey; Murillo, Carlos A .; Bochmann, Manfred Advanced Inorganic Chemistry 6th ed. New York, NY: John Wiley, 1999.

Assessment method:
Oral: The oral exam (about 45 minutes) aims to evaluate the preparation on the whole program, starting with a detailed analysis of a literature article (relevant to the program) at the choice. Students' knowledge of organometallic chemistry along with its application to synthetic organic reactions, and their ability to apply them to problems will be assessed.

Language of instruction
Italian
English if required

Attendance Policy:
Strongly recommended

Mode of teaching:

Traditional (frontal lessons, however, all the material presented in lessons is made available to students via the web page and constantly updated)

Website:
http://acasellicm.ariel.ctu.unimi.it/v3/home/Default.asp