Biomedical sciences 1

A.Y. 2019/2020
Overall hours
BIO/09 BIO/10
Learning objectives
- to learn the molecular and biochemical mechanisms underlying basic life processes and their metabolic correlates
- to learn organic functions with a particular emphasis on the nervous system, their dynamic integration and the general control mechanisms in physiological conditions
- to learn the fundamental functional parameters in healthy conditions.
Expected learning outcomes
- The knowledge of molecular, metabolic and biochemical mechanisms supporting physiological functions
- The knowledge of the general principles of brain functioning and of its integration with other organs in physiological conditions
- The acquisition of the fundamental parameters n healthy conditions.
Course syllabus and organization

Single session

Prerequisites for admission
Fundamentals of physics and biology
Assessment methods and Criteria
Multiple choice written exam.
The results will be communicated by vweb
Course syllabus
Resting membrane potential, ionic channels, local passive properties and action potential
The synapse
Sensory systems
Neuromuscular transmission
Motor systems
Cerebellum and basal ganglia
Sleep and consciousness
Teaching methods
Lectures supported by powerpoint presentations.
Teaching Resources
Dee U. Silverthorn Fisiologia Umana: un approccio integrato. Ed. Pearson
Course syllabus
Overview of Chemistry. General chemistry: atomic structure and periodic table. Chemical bonds. Chemical reactions. Structure and properties of water. Solutions. pH and buffers. Organic chemistry: chemical properties of carbon. Functional groups and reactions. Isomerism.
Biochemistry. Aminoacids and proteins: structure and function. Hemoglobin and Myoglobin. Enzymes: general properties, catalysis, kinetics and inhibition, regulation. Carbohydrates: structure and function. Monosaccharides: classification, configuration. Disaccharides: glycosidic bond. Polysaccharides: starch, cellulose and glycogen. Lipids: structure and function. Saturated and unsaturated fatty acids. Triglycerides. Phospholipids. Steroids: structure and functions of cholesterol. Nucleic acids: nucleosides and nucleotides. Structure of ATP, acetyl-CoA and adenine coenzymes. Biological membranes: structure and function. Membrane transport. General principles of metabolism: anabolic and catabolic pathways. Introduction to thermodynamics. Fundamentals of bioenergetics. Carbohydrate metabolism: glycolysis, fate of pyruvate. The citric acid cycle. Metabolism of proteins, urea cycle. Metabolism of lipids: metabolism of triglycerides, fate of acetyl-CoA, β-oxidation, ketone bodies, biosynthesis of fatty acids. Introduction to neurotransmitters and their biosynthesis.
Teaching methods
Lectures supported by powerpoint presentations.
Teaching Resources
Michele Samaja Rita Paroni Chimica e Biochimica. Per le lauree triennali dell'area biomedica ed Piccin
- Massimo Stefani Niccolò Taddei Chimica e Biochimica ed Zanichelli
BIO/10 - BIOCHEMISTRY - University credits: 2
Lessons: 20 hours
Professor: Casati Silvana
BIO/09 - PHYSIOLOGY - University credits: 2
Lessons: 20 hours
Professor: Massimini Marcello