Biophysiology of reproduction, sexology and andrology

A.Y. 2019/2020
Overall hours
MED/03 MED/13 MED/40 MED/50
Learning objectives
Provide students with the main scientific knowledge of reproduction biophysiology, sexology, medical andrology, and preconceptional eugenics.
Know the main problems concerning women's health such as fertility regulation, preconceptional health, menopause, genital infections, diagnostic and surgical techniques of the main benign gynecological pathologies.
Know the methods of family planning and methods of sex education.
Know the mechanisms of transmission and expression of genetic information, in particular preconception screening methods and the main genetic pathologies.
Know the structural and relational vision of couples, families and groups.
Know the definitions of sexuality and its functions and the tools to recognize risk situations related to sexual violence and maltreatment
Expected learning outcomes
Perform a clinical reasoning aimed at identifying the main pathologies studied during the course, to Recognize the most frequent forms of gynecological, endocrinological and genetic diseases, and to Promote prevention and health education related to them. They will also have acquired skills related to the professional figure of the Health Assistant and the ability to apply the acquired knowledge
Course syllabus and organization

Single session

Prerequisites for admission
There are no prerequisites
Assessment methods and Criteria
Oral examination
All the exams take place on the same day.
Ginecologia e ostetricia
Course syllabus
· Anatomy of the female genital tract
· Physiology and pathology of the menstrual cycle
· Contraception: natural and pharmacological methods for controlling fertility
· Infertility and assisted reproduction
· Abortion
· The climacteric: clinical and therapeutic aspects
· Gynecological emergencies: adnexal torsion, hemorrhagic corpus luteum, pelvic inflammatory disease, ectopic pregnancy
· Genital tract infections
· Benign gynecological pathology: fibroids, polyps, ovarian cysts, endometriosis
· Early diagnosis of cervical tumors (HPV)
· Prenatal diagnosis: amniocentesis, villocentesis, bi-test, DNA test
· Instrumental diagnostics in gynecology: gynecological ultrasound, colposcopy, hysteroscopy
Teaching methods
Frontal Lessons
Teaching Resources
Ginecologia e Ostetricia - di Zanoio - Barcellona - Zacche' (ediz. MASSON)
La clinica ostetrica e ginecologica - di Candiani Giovanni B. Vittorio Danesino Attilio Gastaldi (ediz. Elsevier)
Ginecologia e Ostetricia - di Zanoio - Barcellona - Zacche' (ediz. MASSON)
La clinica ostetrica e ginecologica - di Candiani Giovanni B. Vittorio Danesino Attilio Gastaldi (ediz. Elsevier)
Course syllabus
Introduction to the course;
- Introduction to the Endocrine System;
- Classification of hormones and their mechanisms of action;
- Description of the hypothalamic-pituitary system and functioning of the hypothalamic-pituitary axes with particular attention to the hypothalamic-pituitary-gonadal axis;
- Sexual differentiation and gonadal development: determination of chromosomal sex, gonadal sex, phenotypic sex and psychological sex; Classification of sexual differentiation disorders: Klinefelter syndrome, Turner syndrome
- Puberty: physiology, precocious puberty and delayed puberty.
- Ovarian physiology: synthesis and function of estrogen and progesterone; description of the menstrual cycle.
- Description of primary and secondary, hypo-/hyper- and normogondatropic amenorrhea.
- Polycystic ovary syndrome
- Hyperprolactinemic syndromes
- Fertility and thyroid
- Pregnancy and thyroid function
- Physiological and iatrogenic menopause, Premature ovarian failure.
- Peripheral and central male hypogonadism, male late-onset hypogonadism (LOH)
- Cryptorchidism, varicocele
- Gynecomastia
- Erectile dysfuntcion
- Testis tumors
Teaching methods
Frontal Lessons
Teaching Resources
- Malattie del sistema endocrino e del metabolismo 5/ed - MacGraw-Hill. Autori: G. Faglia, P. Beck-Peccoz, A. Spada
- Core curriculum. Endocrinologia e metabolismo - MacGraw-Hill. Autori: G. Faglia, P. Beck-Peccoz, A. Spada, A. Lania
Genetica medica
Course syllabus
Human karyotype:
- Chromosome structure, function and classification
- Somatic cell division: the mitosis
- Germ cell division: the meiosis
- Spermatogenesis and ovogenesis
- Numerical chromosome abnormalities: non-disjunction at meiosis I and II
- Balanced and unbalanced structural chromosome abnormalities

- Genetic sex determination: the importance of SRY gene
- Genetic causes of male and female infertility

- Genetic inheritance:
- Dominant and recessive traits
- Monogenic diseases inheritance: the study of family trees

- Introduction to prenatal diagnosis
- Invasive vs non-invasive prenatal test
- Issues related to prenatal diagnosis

- Genetic tests and genetic counselling
Teaching methods
Whole class teaching
Teaching Resources
"Genetica Medica Essenziale" Dallapiccola-Novelli, CIC Edizioni Internazionali
Scienze tecniche mediche applicate
Course syllabus
- definition of sexuality linked to culture, age and function
- basics about human right sexuality like knowldage for reduce blocks that limit of right's freedom
- sexual experience in the frail elderly age
- anatomical and physiological changes in men and women related to sexuality in the elderly
- cycle of sexual response in the elderly
- chronic diseases that influence rhe sexual sphere
- sexual experience in adulthood
- pregnancy, sexuality, culture
- fatherhood and sexuality culture
- relational aspects and sexuality, culture
- complex case exercise with skills development related to teamwork: sexual desire disorder, arousal disturbance, orgasm disorder, contentment disturbance.

For each disturbance will be identified the main ones involving people divided by gender, age or culture
Teaching methods
Frontal Lessons and practical sessions
Teaching Resources
Simonelli C., Psicologia dello sviluppo sessuale e affettivo, Carocci Editore, 2008
Simonelli C., Sessuologia clinica. Diagnosi, trattamento e linee guida internazionali, Franco Angeli, 2019
Pellai A., Educazione sanitaria. Principi, modelli, strategie e interventi. Manuale per insegnanti ed operatori socio-sanitari, Franco Angeli, 2006
Pellai A. Da uomo a padre. Il percorso emotivo della paternità, Mondatori, 2019
Pellai A., L'attesa. Il percorso emotivo della gravidanza, Erikson, 2013
Marion P., Il disagio del desiderio, Donzelli, 2017
Graziottin A. Sexual function in women with gynecologic cancer. It J Gynec Obstet 2001
AAVV Report of the International Consensus Development Conference on female sexual dysfunction: Definition and Classification. Journal of Urology 2000;
evento formativo n. 265205 , edizione n° 1 dal titolo " L'INCIDENZA DELLA CLINICA SULLA SFERA SESSUALE, Cantù in via Brianza, Ottobre 2019
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 2
Lessons: 20 hours
Genetica medica
MED/03 - MEDICAL GENETICS - University credits: 1
Lessons: 10 hours
Ginecologia e ostetricia
MED/40 - OBSTETRICS AND GYNAECOLOGY - University credits: 1
Lessons: 10 hours
Professor: Vignali Michele
Scienze tecniche mediche applicate
Lessons: 20 hours
Professors: Ceriotti Chiara, Fadelli Sara
Friday 14-15 (appointment requested)
IRCCS Istituto Auxologico Italiano - Ospedale San Luca (5°piano) - Piazzale Brescia 20 - 20149 Milano