Formulation and Legislation of Health Products
A.Y. 2019/2020
Learning objectives
The purpose of the course is to provide basics concepts on formulation, preparation/production and quality control health products, particularly with regard to dietary supplements, and on current legislation and regulations thereof.
Expected learning outcomes
At the end of the course the student will acquire skills to prepare health products such as dietary supplements, according to the current legislation and regulations. Training in the lab will consolidate the theoretical notions previously provided.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Lesson period
First semester
Course syllabus
- Introduction
- Dosage forms. Definition and classification. Administration routes
- Biopharmaceutics: LADME processes, descriptive pharmacokinetic parameters, absolute and relative bioavailability
- Powders: properties and characterization
- Unitary operations (grinding, mixing and drying): rationale, mechanisms, equipment
- Granulation: rationale, mechanisms, equipment
- Compression: compression physics, equipment setting
- Formulation and preparation of solid dosage forms: tablets, capsules, lozenges, chewing gums. Technological and biopharmaceutical tests
- Coating of solid dosage forms
- Modified-release dosage forms for oral administration
- Formulation and production factors that affect bioavailability. Solid State. Noyes -Whitney's Equation
- Formulation and preparation of liquid oral dosage forms
- Notes on stability of solid and liquid dosage forms
- Dosage forms. Definition and classification. Administration routes
- Biopharmaceutics: LADME processes, descriptive pharmacokinetic parameters, absolute and relative bioavailability
- Powders: properties and characterization
- Unitary operations (grinding, mixing and drying): rationale, mechanisms, equipment
- Granulation: rationale, mechanisms, equipment
- Compression: compression physics, equipment setting
- Formulation and preparation of solid dosage forms: tablets, capsules, lozenges, chewing gums. Technological and biopharmaceutical tests
- Coating of solid dosage forms
- Modified-release dosage forms for oral administration
- Formulation and production factors that affect bioavailability. Solid State. Noyes -Whitney's Equation
- Formulation and preparation of liquid oral dosage forms
- Notes on stability of solid and liquid dosage forms
Prerequisites for admission
-Chemistry
- Phytopharmaceutical analysis
- Phytopharmaceutical analysis
Teaching methods
Frontal lessons, single-bench practices and presentation of audiovisual support material
Teaching Resources
Support material for the study is available on Ariel website
Assessment methods and Criteria
There will be a written test consisting of 2/3 questions on general topics, time available about 50 minutes; all questions must be answered with a score of at least 18/30. The outcome of the written test and the planning of the oral one are communicated within a maximum of 3 days; There is also an oral test consisting of 2/3 questions on specific topics covered in the course.
CHIM/09 - PHARMACEUTICAL AND TECHNOLOGICAL APPLICATIONS OF CHEMISTRY - University credits: 6
Single bench laboratory practical: 16 hours
Lessons: 40 hours
Lessons: 40 hours
Professor:
Ochoa Evelyn
Shifts:
-
Professor:
Ochoa Evelyn