Internal Medicine and Pharmacological Bases of Therapy

A.Y. 2019/2020
9
Max ECTS
90
Overall hours
SSD
BIO/14 MED/09 MED/34
Language
Italian
Learning objectives
- Knowing the basics of drug action and their effects
- Knowing and being able to describe the general basis of the diseases, the main systemic and organ pathological conditions with particular regard to: etiology, epidemiology, pathophysiological mechanisms, clinical manifestations and therapeutic strategies
- Knowing the specific terminology for understanding and communication in a clinical work context
- Knowing the fundamentals of physical medicine and rehabilitation of motor activities in developmental age, with in-depth studies in physchiatry, orthopedy and kinesiology
Expected learning outcomes
The student must understand and be able to explain:
- the basis of drug action and of their effects;
-the main systemic and organ pathological conditions with particular regard to: etiology, outline of epidemiology, pathophysiological mechanisms, clinical manifestations and diagnostic and therapeutic pathways;
- the fundamentals of physical medicine and rehabilitation of motor activities in the developmental age.
The student must demonstrate mastery of the specific terminology for understanding and communication in a clinical work context.
Course syllabus and organization

Sezione: Bosisio Parini

Prerequisites for admission
Basic concepts of chemistry, biochemistry, pathology and human physiology.
Assessment methods and Criteria
Written test with multiple choice questions and oral exam.
Farmacologia
Course syllabus
Receptor drug interactions
Effect of drugs, receptor agonists and antagonists - Generalities on receptors
tyrosine kinase receptors
Receptors coupled with heterotrimetric G proteins
Cell death and apoptogenic receptors
Ionotropic receptors pumps and drug transporters
Secretion, desensitization and downregulation of receptors
Pharmacokinetics, absorption and distribution of drugs
Pharmacokinetics, metabolism and elimination of drugs
Calcium homeostasis and calcium channel blockers
Nitroderivatives and nitric oxide
NSAIDs and arachidonic acid
Corticosteroids and related receptors
Teaching methods
Lectures of a dialectical type, supported by the use of the chalk board for the parts involving signal transduction pathways as well as slides for complex representations.
Teaching Resources
Govoni - Farmacologia, Casa editrice Ambrosiana
AA VV - Farmacologia generale e molecolare a cura di F. Clementi e G Fumagalli, editore Edra SpA
Medicina interna
Course syllabus
Pneumology
Gastroenterology
Nephrology
Endocrinology
Hematology
Angiology
Cardiology
Each one will be treated: etiology, epidemiology, physio pathological mechanisms, clinical manifestations and diagnostic-therapeutic pathways
Teaching methods
Lectures accompanied by slides delivered to the students at the end of the teaching cycle.
Teaching Resources
Anatomia per le professioni sanitarie, AAVV, Casa Ed. Idelson-Gnocchi (Sorbona)
Fisiologia Umana: un approccio integrato, Autore: Silverthorn, Casa Ed. Pearson
Patologia Generale e Fisiopatologia per le professioni sanitarie, Autore: Jeanette Maier, Casa Ed. Mc Graw Hill
Medicina fisica e riabilitativa
Course syllabus
Cerebral palsy
Idiopathic and secondary scoliosis
Skeletal dysplasias.
Rehabilitation diagnosis, therapeutic planning, physiotherapy and orthotic treatment
Teaching methods
Lectures with slides that will be used as didactic support by the students. Bibliographic sources are included on the slides.
Teaching Resources
Diapositive delle lezioni in cui sono indicate le fonti bibliografiche (Slides of the lecture in which the bibliographic sources are indicated).
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 40 hours
Medicina fisica e riabilitativa
MED/34 - PHYSICAL AND REHABILITATION MEDICINE - University credits: 2
Lessons: 20 hours
Professor: Fraschini Paolo
Medicina interna
MED/09 - INTERNAL MEDICINE - University credits: 3
Lessons: 30 hours

Sezione: Don Gnocchi

Prerequisites for admission
Basic knowledge of chemistry, biochemistry, pathology and human physiology.
Assessment methods and Criteria
Written test with open or multiple choice questions and oral exam.
Farmacologia
Course syllabus
Pharmacokinetics
Pharmacodynamics
Drug interactions
The synapse and the autonomic nervous system
Antiepileptic drugs
Antidepressant medications
Narcotic analgesic drugs
Anabolic drugs
Drugs of abuse and anxiolytics
Neuroleptic and psychostimulant drugs
Drugs and methodologies effective in re-opening neuronal plasticity
Anti-inflammatory and active drugs on neuro-inflammation
Teaching methods
Lectures with the support of specific didactic materials.
Teaching Resources
Cella, Di Giulio, Gorio, Scaglione - Farmacologia generale e speciale per le lauree sanitarie - Piccin-Nuova Libraria, 2010
Medicina interna
Course syllabus
PNEUMOLOGY
Infectious pathology of the respiratory system
Chronic obstructive pulmonary disease (chronic bronchitis, asthma, emphysema)
-Cystic fibrosis
2. GASTRO-ENTEROLOGY
Malabsorption, celiac disease
Chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis)
Pathophysiology and classification of jaundices
Acute and chronic hepatitis
3. NEPHROLOGY
Glomerular, tubular and interstitial pathologies
Acute and chronic renal failure
Infections of the kidney and urinary tract, urinary stones
4. ENDOCRINOLOGY
Thyroid pathologies
Diabetes I and II
Metabolic syndrome
5. HEMATOLOGY
Anaemia
Pathologies of haemostasis and coagulation
6. ANGIOLOGY
Venous thrombosis
Chronic venous insufficiency
Peripheral arterial disease
7. CARDIOLOGY
Heart rhythm disorders: outline
Ischemic heart disease
Main congenital heart disease
Heart failure
Teaching methods
Lectures with the support of specific didactic materials.
Teaching Resources
Vengono messi a disposizione tutti i materiali utilizzati a lezione sotto forma di file pdf disponibili online (All the materials used in class are made available online in the form of pdf files).
Per approfondimenti (To further information): R. Massini et al. Medicina Interna (4a Ed., 2009) McGraw Hill.
Medicina fisica e riabilitativa
Course syllabus
Evolution of the erected station
Evolution of the human journey
Walk parameters, lameness
Scoliosis
Osteochondrosis
Epiphysiolysis
Evolutionary dysplasia of the hip
Congenital clubfoot
Osteomyelitis in the new-born and child
Obstetric trauma, obstetric paralysis
Congenital stiff neck.
Cranial dysmorphisms of the new-born.
Principles of traumatology
Teaching methods
Lectures with the support of specific didactic materials.
Teaching Resources
Materiale didattico utilizzato a lezione (diapositive, articoli scientifici). Teaching material used in class (slides, scientific articles).
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 40 hours
Professor: Antonucci Flavia
Medicina fisica e riabilitativa
MED/34 - PHYSICAL AND REHABILITATION MEDICINE - University credits: 2
Lessons: 20 hours
Medicina interna
MED/09 - INTERNAL MEDICINE - University credits: 3
Lessons: 30 hours
Professor: Catalano Maria
Professor(s)
Reception:
on appointment to be organised via e-mail
"Palazzina LITA-Vialba"