Pathogenetic bases of neurological and psychiatric disorders

A.Y. 2019/2020
Overall hours
BIO/11 MED/13 MED/25 MED/26
Learning objectives
To provide to the students the current knowledge of the pathogenetic mechanism, causes and clinical implication of the principal neurological and psychiatric disorders. To acquire the advances in the biological research in these fields. To understand how these diseases can affect the life expectations and autonomy of affected patients.
Expected learning outcomes
The comprehension of the pathological mechanisms underlying neurological and psychiatric disorders. To understand where the research on the pathogenetic mechanisms has arrived and what are the current field of biological research and what are the perspective in the study of these diseases.
Course syllabus and organization

Single session

Lesson period
Third trimester
Course syllabus
Molecular biology:
Genetics of neuropsychiatric disorders
Epigenetic mechanisms in neuropsychiatric disorders
Advanced experimental models of neuropsychiatric disorders
Therapeutic inroads for neuropsychiatric disorders.
Physiopathology of anterior pituitary and hypothalamic system
Physiopathology of the posterior pituitary gland
Neuroendocrinology of appetite and weight control.
Mental health:
The concept of mental disease based on DSM-5 and the Psychic Objective Exam
The basis of psychopathology I
The basis of psychopathology II
Psycosis and schizophrenia
Depression and Bipolar disorders
Anxiety Disorders and Obsessive Compulsive Disorders
Personality and Developmental Disorders
Cognitive and Neural basis of the major psychiatric disorders.
Cerebrovascular diseases
Infective disorders
Multiple sclerosis
Alzheimer disease and other Dementias
Parkinson's Disease
Amyotrophic lateral sclerosis
Prerequisites for admission
Students must have knowledge of the anatomy, physiology and biochemistry of the central and peripheral nervous system and of the related endocrinologic system.
Teaching methods
The teaching course is based on frontal seminars covering all the main pathological mechanisms and clinical implications of the principal neurological and psychiatric disease. Students will be provided all the slides of each lecture.
The student is required to attend all the teaching activities, with a tolerance of no more than 25% of the hours. Students are required to sign their attendance at each learning activities. Should the number of absences be higher than 25%, the Teaching Committee will take the necessary measures.
Teaching Resources
Slides provided by the teachers
Kandel et al. Principle of Neurosciences
Assessment methods and Criteria
The examination will be an oral assessment performed in all the disciplines covered by the course. The final vote will result from the weighted average of different examinations with a final score of 0-30 and will take in consideration not only the knowledge of each discipline but also the quality and clarity of the responses
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 1
Lessons: 7 hours
Mental health
MED/25 - PSYCHIATRY - University credits: 2
Lessons: 14 hours
Professor: Brambilla Paolo
Molecular biology
BIO/11 - MOLECULAR BIOLOGY - University credits: 1
Lessons: 7 hours
Professor: Testa Giuseppe
MED/26 - NEUROLOGY - University credits: 2
Lessons: 14 hours
based on appointment
Via Della Commenda, 10/12 - Ospedale Maggiore Policlinico - Pad. Alfieri, first floor