Vaccinology
A.Y. 2019/2020
Learning objectives
The course aims to provide a comprehensive and integrated overview in the important field of vaccinology, from immunology to all types of vaccine development, production, delivery and effect evaluation, including also the approaches for plant transformation (GMO and production of heterologous proteins)
Expected learning outcomes
The student is expected to reach the following results:
Theoretical learning
Gain knowledge on:
- Different types of veterinary vaccines and routes of vaccination
- Methodologies to prepare each type of vaccine, including oral vaccines
- Effects of vaccines in inducing specific and protective immune response
- Genetic modification of crops and medical molecular farming
- Key risk assessment and advantages of edible vaccines in veterinary medicine
Practical learning
- Know how to plan and prepare at least for phase 1 (in laboratory) a vaccine
- Know routes and time to perform vaccination
- Evaluation of genetically modified plants
- Ability to assess the effect of vaccination
Theoretical learning
Gain knowledge on:
- Different types of veterinary vaccines and routes of vaccination
- Methodologies to prepare each type of vaccine, including oral vaccines
- Effects of vaccines in inducing specific and protective immune response
- Genetic modification of crops and medical molecular farming
- Key risk assessment and advantages of edible vaccines in veterinary medicine
Practical learning
- Know how to plan and prepare at least for phase 1 (in laboratory) a vaccine
- Know routes and time to perform vaccination
- Evaluation of genetically modified plants
- Ability to assess the effect of vaccination
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Prerequisites for admission
Not required any preliminary knowledge
Assessment methods and Criteria
The obtainment of the expected learning outcomes by the student are assessed by an oral examination based on questions with open answer and questions with closed answer, which include also the description of the practical activity.
The evaluation parameters include correctness of answer, comprehension of the topics of the program, ability to connect them and propriety of language.
The grade is expressed in thirtieths and it is communicated to the student immediately after the end of the oral exam.
The evaluation parameters include correctness of answer, comprehension of the topics of the program, ability to connect them and propriety of language.
The grade is expressed in thirtieths and it is communicated to the student immediately after the end of the oral exam.
Module: Innovative vaccine development and production
Course syllabus
Ricombinant vaccines development strategies
Subunit vaccines and Adjuvants (including liposomes, ISCOMs and VLPs)
Live attenuated recombinant vaccines
Genetic vaccines (DNA and RNA)
Innovative approaches (CpG motifs, peptide vaccines and others)
Subunit vaccines and Adjuvants (including liposomes, ISCOMs and VLPs)
Live attenuated recombinant vaccines
Genetic vaccines (DNA and RNA)
Innovative approaches (CpG motifs, peptide vaccines and others)
Teaching methods
The teaching consists in theoretical classes and practical classes
Teaching Resources
Handouts will be provided by the teacher through ARIEL website
Module: Practical aspects of vaccinology
Course syllabus
History, passive & active immunization.
Veterinary vaccine development: from idea to delivery; market, registration and pharmacovigilance
Types of veterinary vaccines: from traditional to modern drugs
Field application of human and veterinary vaccines, herd immunity
Vaccine side effects: truth & hoax
Veterinary vaccine development: from idea to delivery; market, registration and pharmacovigilance
Types of veterinary vaccines: from traditional to modern drugs
Field application of human and veterinary vaccines, herd immunity
Vaccine side effects: truth & hoax
Teaching methods
The teaching consists in theoretical classes and practical classes
Teaching Resources
Handouts will be provided by the teacher through ARIEL website
Module: Plant-based production of oral vaccines
Course syllabus
Plant transformation tools: Agrobacterium-mediated (stable and transient) and biolistic approach
Biomass Production and evaluation of heterologous antigenic protein expression: the example of tobacco plants
An example of application: pigs fed a tobacco seed based oral vaccines
Biomass Production and evaluation of heterologous antigenic protein expression: the example of tobacco plants
An example of application: pigs fed a tobacco seed based oral vaccines
Teaching methods
The teaching consists in theoretical classes and practical classes
Teaching Resources
Handouts will be provided by the teacher through ARIEL website
Module: Innovative vaccine development and production
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 3
Lessons: 18 hours
Professor:
Turin Lauretta
Shifts:
-
Professor:
Turin Lauretta
Module: Plant-based production of oral vaccines
AGR/18 - ANIMAL NUTRITION AND FEEDING - University credits: 2
Lessons: 12 hours
Professor:
Rossi Luciana
Shifts:
-
Professor:
Rossi Luciana
Module: Practical aspects of vaccinology
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 3
Lessons: 18 hours
Professor:
Dall'Ara Paola Emanuela Maria
Shifts:
-
Professor:
Dall'Ara Paola Emanuela MariaProfessor(s)
Reception:
contact me by mail or phone
Reception:
Monday 9:00 a.m. - 1 p.m.
Polo Lodi