Chemistry and Biochemistry
A.Y. 2020/2021
Learning objectives
The course aims to provide students with the knowledge of the fundamental concepts of chemistry and biochemistry underlying the metabolism and functionality of the organism.
Expected learning outcomes
Students:
a) know the fundamental principles of molecular, cellular and biochemical mechanisms related to the body's patho-physiology;
b) understand the importance of applying the concepts of basic research to translational research;
c) they approach critically the international scientific literature to write short review on specific topics.
a) know the fundamental principles of molecular, cellular and biochemical mechanisms related to the body's patho-physiology;
b) understand the importance of applying the concepts of basic research to translational research;
c) they approach critically the international scientific literature to write short review on specific topics.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
In the first semester the lectures will take place as concurrent classroms:
·in the classroom with a limited number of students, who have previously booked using the "lezioniUnimi" app with the unimi e-mail account username and password; (https://www.unimi.it/it/studiare/frequentare-un-corso-di-laurea/seguire-il-percorso-di-studi/orari-delle-lezioni) and at the same time through the "Teams platform" for online students ;
· The student must wear a surgical mask for the entire duration of his/her stay in the classroom and to sit using every other free seat
· the lectures will be recorded and made available on the teacher's Ariel website for students with proven difficulties to connect during classes
· the lectures will take place at the San Paolo Hospital on the 3rd floor of Blocco C. Students must access classrooms via Blocco C and exit via the side blocks (students leaving Pauling and Fleming rooms towards Blocco B and students leaving Curie, Golgi and Pasteur rooms towards Blocco A).
Students must enter from the main hall (R floor) of the San Paolo hospital and undergo body temperature measurement by the infrared cameras. It is strongly recommended to use the stairs for classrooms entering and/or leaving.
NB for any further information check the unimi.it website: (Home Studiare Frequentare un corso di laurea Seguire il percorso di studi Orari delle lezioni)
·in the classroom with a limited number of students, who have previously booked using the "lezioniUnimi" app with the unimi e-mail account username and password; (https://www.unimi.it/it/studiare/frequentare-un-corso-di-laurea/seguire-il-percorso-di-studi/orari-delle-lezioni) and at the same time through the "Teams platform" for online students ;
· The student must wear a surgical mask for the entire duration of his/her stay in the classroom and to sit using every other free seat
· the lectures will be recorded and made available on the teacher's Ariel website for students with proven difficulties to connect during classes
· the lectures will take place at the San Paolo Hospital on the 3rd floor of Blocco C. Students must access classrooms via Blocco C and exit via the side blocks (students leaving Pauling and Fleming rooms towards Blocco B and students leaving Curie, Golgi and Pasteur rooms towards Blocco A).
Students must enter from the main hall (R floor) of the San Paolo hospital and undergo body temperature measurement by the infrared cameras. It is strongly recommended to use the stairs for classrooms entering and/or leaving.
NB for any further information check the unimi.it website: (Home Studiare Frequentare un corso di laurea Seguire il percorso di studi Orari delle lezioni)
Course syllabus
Inorganic chemistry
The material and the atomic structure.
The chemical bonds between atoms and molecules.
The physical state of the material.
The aqueous solutions.
The equilibrium of the chemical reactions.
The acid and basic compounds.
The buffer compounds.
Principles of electrochemistry.
Organic Chemistry
The saturated/unsaturated hydrocarbons. Alkanes, alkenes, cycloalkanes, aromatic compounds.
Functional groups. alcohols, phenols, tio alcohols, amines, carbony compounds (aldehydes and ketones),
carboxylic acids and derivatives.
Preparatory biochemistry
The carbohydrates
The lipids
The proteins
The nucleic acids
The enzymes
Metabolic Biochemistry
Oxygen transport and chromo-proteins
Vitamins and coenzymes
Structure and functions of biological membranes
Mitochondria bioenergy
Carbohydrate metabolism
Lipid Metabolism
Hemoglobin metabolism
Nucleotides metabolism
Liver biochemistry
The material and the atomic structure.
The chemical bonds between atoms and molecules.
The physical state of the material.
The aqueous solutions.
The equilibrium of the chemical reactions.
The acid and basic compounds.
The buffer compounds.
Principles of electrochemistry.
Organic Chemistry
The saturated/unsaturated hydrocarbons. Alkanes, alkenes, cycloalkanes, aromatic compounds.
Functional groups. alcohols, phenols, tio alcohols, amines, carbony compounds (aldehydes and ketones),
carboxylic acids and derivatives.
Preparatory biochemistry
The carbohydrates
The lipids
The proteins
The nucleic acids
The enzymes
Metabolic Biochemistry
Oxygen transport and chromo-proteins
Vitamins and coenzymes
Structure and functions of biological membranes
Mitochondria bioenergy
Carbohydrate metabolism
Lipid Metabolism
Hemoglobin metabolism
Nucleotides metabolism
Liver biochemistry
Prerequisites for admission
High school scientific skills.
Teaching methods
Lectures, exercise training, team works.
Teaching Resources
- Santaniello E., Coletta M., Malatesta F., Zanotti G., Marini S., "Chimica Propedeutica alle scienze bio-mediche", Ed. Piccin
- Bellini T., "Chimica medica e propedeutica biochimica", Ed. Zanichelli
- Bettelheim F.A., Brown W.H., Campbell M.K., Farrell S.O., "Chimica e propedeutica biochimica", Ed. Edises
- Biochimica Medica Siliprandi e Tettamanti (PICCIN)
- Biochimica con aspetti clinici, Devlin, Edises
- Biochimica Medica , Lieberman e Marks, Casa Editrice Ambrosiana
- Bellini T., "Chimica medica e propedeutica biochimica", Ed. Zanichelli
- Bettelheim F.A., Brown W.H., Campbell M.K., Farrell S.O., "Chimica e propedeutica biochimica", Ed. Edises
- Biochimica Medica Siliprandi e Tettamanti (PICCIN)
- Biochimica con aspetti clinici, Devlin, Edises
- Biochimica Medica , Lieberman e Marks, Casa Editrice Ambrosiana
Assessment methods and Criteria
Two written tests and one oral test
Use of the periodic table of the elements and calculator
Test score will be published on Ariel website
Use of the periodic table of the elements and calculator
Test score will be published on Ariel website
BIO/10 - BIOCHEMISTRY - University credits: 12
Lessons: 144 hours
Professors:
Caretti Anna, Signorelli Paola
Professor(s)
Reception:
To be defined via e-mail
c/o Osp. San Paolo, Via A. di Rudinì 8, Laboratorio di Biochimica, 9 piano, Blocco C,