Clinical Biochemistry
A.Y. 2020/2021
Learning objectives
The teaching aims to provide students with theoretical and practical knowledge for the understanding and use of current laboratory tests, through the knowledge of analytical principles, optimization processes and their interpretation.
Expected learning outcomes
At the end of the course, the student will acquire the knowledge of the analytical principles at the base of the most frequent laboratory tests, on the processes for the optimization of laboratory tests, on the current events in the market of national and international diagnostic producers. From a communicative point of view, the student will be able to explain and interpret the chemical-clinical examinations. The course will provide the basic principles to facilitate the future integration of Biologists in the field of Laboratory Medicine.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
Teaching methods
Lessons will be helded on-line in synchronous mode, on Zoom platform in the scheduled time for this teaching. The recordings of the lessons will be available on the Ariel website. The link to access the lessons on Zoom together with other information and notices, will be uploaded to the Ariel site, students are advised to consult it regularly.
Students interested in attending the lessons, are asked to send an e-mail to the teacher ([email protected]).
Examination procedures
The exam is in written form with three open questions of equal weight regarding the topics addressed during the lessons. The examination will be conducted in presence or on-line through the exam.net platform depending on the directives in force at the time of the exam session.
The examination will be aimed at ascertaining the achievement of the objectives in terms of knowledge and understanding. Students' command of specific terminology as well as their ability to present the topics clearly and logically will also be evaluated.
Reference materials
The program and reference material will not change.
Lessons will be helded on-line in synchronous mode, on Zoom platform in the scheduled time for this teaching. The recordings of the lessons will be available on the Ariel website. The link to access the lessons on Zoom together with other information and notices, will be uploaded to the Ariel site, students are advised to consult it regularly.
Students interested in attending the lessons, are asked to send an e-mail to the teacher ([email protected]).
Examination procedures
The exam is in written form with three open questions of equal weight regarding the topics addressed during the lessons. The examination will be conducted in presence or on-line through the exam.net platform depending on the directives in force at the time of the exam session.
The examination will be aimed at ascertaining the achievement of the objectives in terms of knowledge and understanding. Students' command of specific terminology as well as their ability to present the topics clearly and logically will also be evaluated.
Reference materials
The program and reference material will not change.
Course syllabus
General organization of the clinical laboratory
Pre-analytical phase (sample collection and storage; pre-analytical variability; biological variability)
Analytical variability (evaluation of laboratory methods, quality assurance)
Interpretation of laboratory tests (reference intervals, decisional limits, ROC curves)
Principles of clinical enzymology
Cardiac biomarkers
Tests for liver function
Tests for kidney function
Dislipidemias
Tests for the evaluation of anemias and iron disorders
Tests for laboratory management of diabetes
Biomarkers for bone disorders
Serum proteins and inflammation biomarkers
Tumor markers
Pre-analytical phase (sample collection and storage; pre-analytical variability; biological variability)
Analytical variability (evaluation of laboratory methods, quality assurance)
Interpretation of laboratory tests (reference intervals, decisional limits, ROC curves)
Principles of clinical enzymology
Cardiac biomarkers
Tests for liver function
Tests for kidney function
Dislipidemias
Tests for the evaluation of anemias and iron disorders
Tests for laboratory management of diabetes
Biomarkers for bone disorders
Serum proteins and inflammation biomarkers
Tumor markers
Prerequisites for admission
It is advisable to have acquired basic knowledges of biochemistry and general physiology.
Teaching methods
The course is based on interactive lessons supported by projected materials. Students are stimulated to actively participate to the lecture/discussion in order to improve their critical spirit. This is achieved by carefully looking at the provided literature and by communicating their concepts in an adequate mode. The attendance to the lectures is strongly advised.
Teaching Resources
The presentations of all the lectures are available through the Ariel website, as well as the suggested readings (usually one reading per lecture).
Reference textbooks are the following:
1) Marcello Ciaccio. Elementi di Biochimica Clinica e medicina di laboratorio. EdiSES Università, Napoli,2020.
2) Mauro panteghini. Interpretazione degli esami di laboratorio. Trattato Italiano di Medicina di Laboratorio. Volume VII. Piccin 2008
Reference textbooks are the following:
1) Marcello Ciaccio. Elementi di Biochimica Clinica e medicina di laboratorio. EdiSES Università, Napoli,2020.
2) Mauro panteghini. Interpretazione degli esami di laboratorio. Trattato Italiano di Medicina di Laboratorio. Volume VII. Piccin 2008
Assessment methods and Criteria
Written exam with 3 open questions regarding the topics addressed during the lessons, be completed in 90 min. The evaluation is based on the achievement of a good knowledge of the matter and on the completeness of answers to all the questions. The ability to present the topics clearly and logically will also be evaluated.
No pre-test or intermediate assays are planned. The results are communicated through the dedicated University web-site.
No pre-test or intermediate assays are planned. The results are communicated through the dedicated University web-site.
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 6
Lessons: 48 hours
Professor:
Paleari Renata
Professor(s)