Basic Medical Sciences
A.Y. 2021/2022
Learning objectives
The course aims to provide students with basic knowledge on:
· the concept of human homeostasis at the molecular, cellular and tissue level and the mechanisms aimed at maintaining homeostasis, in the context of the modifications of the surrounding environment
· the principles of sensorimotor physiology
· the neurobiological and psychophysiological concepts related to behavior and interactions between the subject and the environment
· the biological processes at the molecular level, the structure, properties and functions of biomolecules.
· the biochemistry of pathological states
· the human systematic biochemistry
· the molecular and cellular biology
· the morphological characteristics of the systems, apparatuses, organs, tissues of the human organism, as well as their main morpho-functional correlates
· the functional characteristics of the human organs, their dynamic integration into apparatus and the general control mechanisms
· the concept of human homeostasis at the molecular, cellular and tissue level and the mechanisms aimed at maintaining homeostasis, in the context of the modifications of the surrounding environment
· the principles of sensorimotor physiology
· the neurobiological and psychophysiological concepts related to behavior and interactions between the subject and the environment
· the biological processes at the molecular level, the structure, properties and functions of biomolecules.
· the biochemistry of pathological states
· the human systematic biochemistry
· the molecular and cellular biology
· the morphological characteristics of the systems, apparatuses, organs, tissues of the human organism, as well as their main morpho-functional correlates
· the functional characteristics of the human organs, their dynamic integration into apparatus and the general control mechanisms
Expected learning outcomes
At the end of the course the student will have to know:
· the concept of human homeostasis at the molecular, cellular and tissue level and the bases of its mainteinance, in the context of the modifications of the surrounding environment
· the general principles of sensorimotor physiology
· the fundamental neurobiological and psychophysiological concepts related to behavior and interactions between the subject and the environment
· the biological processes at the molecular level, the structure, properties and functions of biomolecules.
· the biochemical bases of pathological states
· the bases of human systematic biochemistry
· the bases of molecular and cellular biology
· the main morphological characteristics of the systems, apparatuses, organs, tissues of the human organism, as well as their main morpho-functional correlates
· the general functional characteristics of the human organs, their dynamic integration into apparatus and the general control mechanisms
· the concept of human homeostasis at the molecular, cellular and tissue level and the bases of its mainteinance, in the context of the modifications of the surrounding environment
· the general principles of sensorimotor physiology
· the fundamental neurobiological and psychophysiological concepts related to behavior and interactions between the subject and the environment
· the biological processes at the molecular level, the structure, properties and functions of biomolecules.
· the biochemical bases of pathological states
· the bases of human systematic biochemistry
· the bases of molecular and cellular biology
· the main morphological characteristics of the systems, apparatuses, organs, tissues of the human organism, as well as their main morpho-functional correlates
· the general functional characteristics of the human organs, their dynamic integration into apparatus and the general control mechanisms
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Sezione: Bosisio Parini
Responsible
More specific information on the delivery modes of training activities for academic year 2021/22 will be provided over the coming months, based on the evolution of the public health situation.
Prerequisites for admission
There are no prerequisites.
Assessment methods and Criteria
Written and oral exam
Physiology
Course syllabus
· Cell membrane: functions, structure, passages of water and solutes, osmosis, transporters, Na+/K+ pump, resting potential
· Excitable tissues: action potential, cable properties, conduction, nerve fibers, synapses, nervous integration
· Muscle: excitation-contraction coupling, mechanics, motor units, motor neurons, force control
· Sensitivity: general properties, thermal sensitivity and pain, tactile sensitivity, proprioception
· Special senses: vision, hearing, equilibrium
· Motor system: spinal cord and reflexes, autonomic nervous system, postural control
· Motor system: structure of the brain, motor cortex and descending pathways, cerebellum, basal ganglia
· Deepening: autonomic nervous system
· Excitable tissues: action potential, cable properties, conduction, nerve fibers, synapses, nervous integration
· Muscle: excitation-contraction coupling, mechanics, motor units, motor neurons, force control
· Sensitivity: general properties, thermal sensitivity and pain, tactile sensitivity, proprioception
· Special senses: vision, hearing, equilibrium
· Motor system: spinal cord and reflexes, autonomic nervous system, postural control
· Motor system: structure of the brain, motor cortex and descending pathways, cerebellum, basal ganglia
· Deepening: autonomic nervous system
Teaching methods
Lectures: 20 hours of basic course + 2 for deepening.
The lessons slides are available on the ARIEL website of the teaching module.
The lessons slides are available on the ARIEL website of the teaching module.
Teaching Resources
- a cura di F. Baldissera e C.A. Porro: "Fisiologia e biofisica medica" vol. I , Poletto Editore
- W.J. Germann, C.L. Stanfield: "Fisiologia", EdiSES
- D.U. Silverthorn: "Fisiologia - un approccio integrato", Casa Editrice Ambrosiana
- L. Zocchi (et al.): "Principi di Fisiologia", EdiSES
- W.J. Germann, C.L. Stanfield: "Fisiologia", EdiSES
- D.U. Silverthorn: "Fisiologia - un approccio integrato", Casa Editrice Ambrosiana
- L. Zocchi (et al.): "Principi di Fisiologia", EdiSES
Biochemistry
Course syllabus
Human body composition
Proteins: structure and function
Enzymes: Enzymatic kinetics; Regulation of enzymatic activity
Biological membranes, composition, organization; Solute Transport across Membranes; Biosignaling: General Features of Signal Transduction
Introduction to Bioenergetics and Metabolism: Compounds with high energy content; Transfer of phosphoryl groups and ATP.
oxygen transport and storage: myoglobin and haemoglobin; Oxidative phosphorylation:
Digestion, absorption and metabolism of carbohydrates
Digestion, absorption and metabolism of lipids
Digestion, absorption and metabolism of proteins
Hormonal regulation of energy metabolism, metabolic integrations between different tissues
Proteins: structure and function
Enzymes: Enzymatic kinetics; Regulation of enzymatic activity
Biological membranes, composition, organization; Solute Transport across Membranes; Biosignaling: General Features of Signal Transduction
Introduction to Bioenergetics and Metabolism: Compounds with high energy content; Transfer of phosphoryl groups and ATP.
oxygen transport and storage: myoglobin and haemoglobin; Oxidative phosphorylation:
Digestion, absorption and metabolism of carbohydrates
Digestion, absorption and metabolism of lipids
Digestion, absorption and metabolism of proteins
Hormonal regulation of energy metabolism, metabolic integrations between different tissues
Teaching methods
The module of biochemistry is a part of the course and includes lectures supported by Power Point presentations . The power point presentations are uploaded into Ariel website.
Teaching Resources
Bibliography will be provided during the lessons
Human anatomy
Course syllabus
The course will open with a lesson that will introduce the meaning of the term "Anatomy", will define the organizational levels of the human body and will focus on the use of the terms necessary to identify an anatomical structure in space.
We will then go on to examine in detail the following devices, taking up, where necessary, the notions regarding the specific histological organization. In particular, we will treat:
- Tegumentary system: skin.
- Skeletal system: bone tissue, axile and appendicular.
- Cardiovascular system: heart, vessels and blood circulation.
- Respiratory system: respiratory tract, lungs and respiratory mechanics.
- Digestive system: oral cavity, alimentary tract and annexed glands (salivary glands, liver and pancreas).
- Urinary system: kidney, urinary tract.
- Nervous system: general characteristics.
We will then go on to examine in detail the following devices, taking up, where necessary, the notions regarding the specific histological organization. In particular, we will treat:
- Tegumentary system: skin.
- Skeletal system: bone tissue, axile and appendicular.
- Cardiovascular system: heart, vessels and blood circulation.
- Respiratory system: respiratory tract, lungs and respiratory mechanics.
- Digestive system: oral cavity, alimentary tract and annexed glands (salivary glands, liver and pancreas).
- Urinary system: kidney, urinary tract.
- Nervous system: general characteristics.
Teaching methods
The human anatomy course is organized in lectures during which the teacher uses Power Point presentations and uses anatomical models of parts of the human body and human organs. Some lessons will also be dedicated to the study of three-dimensional anatomy, using dedicated software and instrumentation. During the course the teacher-students dialogue will be encouraged for clarifications and insights on the topics covered.
Teaching Resources
Martini, Anatomia Umana, EdiSES
Ambrosi, Anatomia dell'uomo, Edi-Ermes
Saladin, Anatomia Umana, Piccin
Tortora, Principi di Anatomia Umana, Casa Editrice Ambrosiana
McKinley, Anatomia Umana, Piccin
Marieb, Elementi di anatomia e fisiologia dell'uomo, Zanichelli
Kapit, Colorare l'anatomia, Piccin
Ambrosi, Anatomia dell'uomo, Edi-Ermes
Saladin, Anatomia Umana, Piccin
Tortora, Principi di Anatomia Umana, Casa Editrice Ambrosiana
McKinley, Anatomia Umana, Piccin
Marieb, Elementi di anatomia e fisiologia dell'uomo, Zanichelli
Kapit, Colorare l'anatomia, Piccin
Biochemistry
BIO/10 - BIOCHEMISTRY - University credits: 1
Lessons: 10 hours
Professor:
Viani Paola
Human anatomy
BIO/16 - HUMAN ANATOMY - University credits: 2
Lessons: 20 hours
Physiology
BIO/09 - PHYSIOLOGY - University credits: 2
Lessons: 20 hours
Professor:
Esposti Roberto Paolo
Sezione: Don Gnocchi
Responsible
More specific information on the delivery modes of training activities for academic year 2021/22 will be provided over the coming months, based on the evolution of the public health situation.
Prerequisites for admission
There are no prerequisites
Assessment methods and Criteria
Written test
Oral exam
Oral exam
Physiology
Course syllabus
· Cell membrane: functions, structure, passages of water and solutes, osmosis, transporters, Na+/K+ pump, resting potential
· Excitable tissues: action potential, cable properties, conduction, nerve fibers, synapses, nervous integration
· Muscle: excitation-contraction coupling, mechanics, motor units, motor neurons, force control
· Sensitivity: general properties, thermal sensitivity and pain, tactile sensitivity, proprioception
· Special senses: vision, hearing, equilibrium
· Motor system: spinal cord and reflexes, autonomic nervous system, postural control
· Motor system: structure of the brain, motor cortex and descending pathways, cerebellum, basal ganglia
· Deepening: autonomic nervous system
· Excitable tissues: action potential, cable properties, conduction, nerve fibers, synapses, nervous integration
· Muscle: excitation-contraction coupling, mechanics, motor units, motor neurons, force control
· Sensitivity: general properties, thermal sensitivity and pain, tactile sensitivity, proprioception
· Special senses: vision, hearing, equilibrium
· Motor system: spinal cord and reflexes, autonomic nervous system, postural control
· Motor system: structure of the brain, motor cortex and descending pathways, cerebellum, basal ganglia
· Deepening: autonomic nervous system
Teaching methods
Lectures: 20 hours of basic course + 2 for deepening.
The lessons slides are available on the ARIEL website of the teaching module.
The lessons slides are available on the ARIEL website of the teaching module.
Teaching Resources
- a cura di F. Baldissera e C.A. Porro: "Fisiologia e biofisica medica" vol. I , Poletto Editore
- W.J. Germann, C.L. Stanfield: "Fisiologia", EdiSES
- D.U. Silverthorn: "Fisiologia - un approccio integrato", Casa Editrice Ambrosiana
- L. Zocchi (et al.): "Principi di Fisiologia", EdiSES
- W.J. Germann, C.L. Stanfield: "Fisiologia", EdiSES
- D.U. Silverthorn: "Fisiologia - un approccio integrato", Casa Editrice Ambrosiana
- L. Zocchi (et al.): "Principi di Fisiologia", EdiSES
Biochemistry
Course syllabus
Human body composition
Proteins: structure and function
Enzymes: Enzymatic kinetics; Regulation of enzymatic activity
Biological membranes, composition, organization; Solute Transport across Membranes; Biosignaling: General Features of Signal Transduction
Introduction to Bioenergetics and Metabolism: Compounds with high energy content; Transfer of phosphoryl groups and ATP.
oxygen transport and storage: myoglobin and haemoglobin; Oxidative phosphorylation:
Digestion, absorption and metabolism of carbohydrates
Digestion, absorption and metabolism of lipids
Digestion, absorption and metabolism of proteins
Hormonal regulation of energy metabolism, metabolic integrations between different tissues
Proteins: structure and function
Enzymes: Enzymatic kinetics; Regulation of enzymatic activity
Biological membranes, composition, organization; Solute Transport across Membranes; Biosignaling: General Features of Signal Transduction
Introduction to Bioenergetics and Metabolism: Compounds with high energy content; Transfer of phosphoryl groups and ATP.
oxygen transport and storage: myoglobin and haemoglobin; Oxidative phosphorylation:
Digestion, absorption and metabolism of carbohydrates
Digestion, absorption and metabolism of lipids
Digestion, absorption and metabolism of proteins
Hormonal regulation of energy metabolism, metabolic integrations between different tissues
Teaching methods
The module of biochemistry is a part of the course and includes lectures supported by Power Point presentations . The power point presentations are uploaded into Ariel website.
Teaching Resources
Bibliography will be provided during the lessons
Human anatomy
Course syllabus
Building principles of the human body
∙ body scheme
∙ hierarchical organization of the human body
∙ general anatomical and functional principles of organic apparatuses
∙ body spaces
∙ construction models of the organs: hollow organs, full organs
Locomotor apparatus
∙ axile skeleton
appendicular skeleton
general information on the joints
general information on the muscles
∙ muscle lodges
∙ chest wall
∙ abdominal wall
Cardiovascular system
∙ heart
blood circulatory system
lymphatic circulatory system
Respiratory apparatus
∙ upper and lower airways
∙ lungs
Digestive apparatus
∙ hollow organs: pharynx, esophagus, stomach, small and large intestine
∙ parenchymatous organs: salivary glands, liver, pancreas
Urinary apparatus
∙ kidney
∙ ureter
∙ bladder and urethra
Male genital apparatus
∙ testicle
∙ spermatic and annexed glands
Female genital apparatus
∙ ovary
∙ genital tract
Endocrine apparatus
∙ pituitary
∙ thyroid and parathyroid glands
∙ adrenal
Nervous system
∙ principles of organization of the axial central nervous system
∙ principles of organization of the supra-axial central nervous system
∙ principles of organization of the peripheral nervous system
∙ principles of organization of the autonomic nervous system
∙ body scheme
∙ hierarchical organization of the human body
∙ general anatomical and functional principles of organic apparatuses
∙ body spaces
∙ construction models of the organs: hollow organs, full organs
Locomotor apparatus
∙ axile skeleton
appendicular skeleton
general information on the joints
general information on the muscles
∙ muscle lodges
∙ chest wall
∙ abdominal wall
Cardiovascular system
∙ heart
blood circulatory system
lymphatic circulatory system
Respiratory apparatus
∙ upper and lower airways
∙ lungs
Digestive apparatus
∙ hollow organs: pharynx, esophagus, stomach, small and large intestine
∙ parenchymatous organs: salivary glands, liver, pancreas
Urinary apparatus
∙ kidney
∙ ureter
∙ bladder and urethra
Male genital apparatus
∙ testicle
∙ spermatic and annexed glands
Female genital apparatus
∙ ovary
∙ genital tract
Endocrine apparatus
∙ pituitary
∙ thyroid and parathyroid glands
∙ adrenal
Nervous system
∙ principles of organization of the axial central nervous system
∙ principles of organization of the supra-axial central nervous system
∙ principles of organization of the peripheral nervous system
∙ principles of organization of the autonomic nervous system
Teaching methods
Classroom-taught
Teaching Resources
Thibodeau, Patton Anatomia Umana I edizione EDRA 2020
Martini, Timmons, Tallitsch Anatomia Umana VII edizione Edises 2019
Saladin Anatomia Umana V edizione Piccin 2017
Martini, Timmons, Tallitsch Anatomia Umana VII edizione Edises 2019
Saladin Anatomia Umana V edizione Piccin 2017
Biochemistry
BIO/10 - BIOCHEMISTRY - University credits: 1
Lessons: 10 hours
Professor:
Viani Paola
Human anatomy
BIO/16 - HUMAN ANATOMY - University credits: 2
Lessons: 20 hours
Professor:
Gibelli Daniele Maria
Physiology
BIO/09 - PHYSIOLOGY - University credits: 2
Lessons: 20 hours
Professors:
Esposti Roberto Paolo, Zocchi Luciano Aldo Maria
Professor(s)
Reception:
By appointment via e-mail, usually on Mondays 10.30am-1.30pm / 2.30pm-5.30pm
By videocall in Microsoft Teams or in presence at the Section Physiology, Dept. Pathophysiology and Transplantation, via L. Mangiagalli 32, Milano - 2nd floor, room n. 10.
Reception:
By appointment via e-mail
Department of Biomedical Sciences for Health, V. Mangiagalli, 31 - Milan