5th year program:
Male urinary and genital system
1. Vascular diseases of the kidney.
2. Infections of the kidney, urinary tract, prostate.
3. Renal, excretory and bladder cancers.
4. Prostatic hypertrophy, prostate adenoma, intraepithelial neoplasia of the prostate, prostate cancer.
5. Neoplastic and non-neoplastic pathology of the testicle.
6. Malformations of the kidney and urinary tract.
7. Anatomopathological instruments for the diagnostic evaluation of the patient with hematuria (macroscopic or microscopic).
1. Gynecological infections: types, anatomopathological features, complications, outcomes.
2. Human papilloma virus (HPV) infection and carcinogenesis in genital and rectal epithelia.
3. Primary preneoplastic and neoplastic lesions of the vulva, vagina and cervix: definitions, epidemiology, biological evolution, risk factors, histotypes, staging, prognostic factors, diagnostic algorithms.
4. The Pap test (conventional and in liquid phase): purpose, target population, method of performing the sampling, diagnostic results, limits; Bethesda's reporting system.
5. Definition of: pavement metaplasia of the uterine cervix, coilocytosis, dysplasia, VIN, VAIN, CIN, carcinoma in situ, minimally invasive carcinoma, superficial growth carcinoma, SIL (low and high grade), ASC-US, ASC-H , AGC.
6. Endometritis and dysfunctional endometriopathy.
7. Endometriosis and adenomyosis.
8. Preneoplastic pathologies of the endometrium: glandular hyperplasia and EIN (endometrial intraepithelial neoplasia).
9. Endometrial carcinoma: epidemiology, biological evolution, risk factors, histotypes, staging, prognostic factors, diagnostic algorithms.
10. Primary non-epithelial benign and malignant neoplasms of the uterine body.
11. Non-neoplastic and neoplastic pathology of the salpingi.
12. Ovarian neoplasms: histogenetic classification, epidemiology, main histotypes, biological evolution, staging, metastasis pathways.
13. "Borderline malignancy"; neoplasm: definition, biological meaning of the term, histological criteria, types of neoplasms in which it is present; neoplasm: definition, biological meaning of the term, histological criteria, types of neoplasms in which it is present.
14. Locations of metastasis of epithelial neoplasms of the vulva, vagina, cervix uteri, uterine body, salpinx, ovaries.
15. Metastasis to the female genital system.
Pathology of pregnancy and gestational trophoblastic pregnancy and post-pregnancy
1. Early and late spontaneous abortion, MEF (fetal endouterine death), perinatal death, neonatal death, I.U.G.R.
1. (symmetrical and asymmetrical), fetus S.G.A .: definition and main anatomical-pathological pictures.
2. Placental and umbilical cord malformations.
3. Characteristics of the "vascular bed of the placenta", its methods of formation and its main pathologies.
4. Placental pathology in the live born fetus and in the stillbirth: structural and maturation alterations; inflammatory / infectious lesions; vascular lesions; neoplastic pathologies; injuries from maternal and fetal pathologies.
5. Gestational and persistent trophoblastic gestational disease: extent, diagnostic criteria, complications, prognosis.
6. Main phenotypic aspects of the most frequent chromosomopathies and gene alterations of the product of conception
Neonatal and pediatric age
1. SUID (sudden and unexpected death) and SIDS (sudden infant death syndrome): characteristics, definition, approach, indications to family members.
2. Anatomopathological aspects of infantile cerebral palsy.
3. Cystic fibrosis.
4. Intestinal dysganglionosis (Hirschsprung disease; NID).
5. Jaline membrane disease and its outcomes.
6. Pediatric lung diseases of surgical interest (in particular: CCAM; pulmonary seizure; congenital emphysema; pleuro-pulmonary blastoma).
1. Primary neoplastic and non-neoplastic lesions of the breast.
2. Locations for metastasis of breast cancer.
Cute and its annexes
1. Inflammatory skin lesions.
2. Bullous skin lesions.
3. Method of conservation and treatment of a skin biopsy in the clinical suspicion of lymphoproliferative disease.
4. Modality of conservation and treatment of a skin biopsy in the differential diagnosis of bullous and autoimmune pathology.
5. Benign and malignant skin epithelial tumors, with particular reference to: wart, seborrheic keratosis, keratoacanthoma, basal cell carcinoma, spinocellular carcinoma.
6. Benign and preneoplastic pigmented lesions of the skin (compound, junctional, dermal, congenital melanocytic nevi, dysplastic nevi).
7. Malignant melanoma: characteristics, prognostic relevance of the different histotypes, of the growth modalities and of the staging according to Clark and according to Breslow.
8. Methods and main sites of metastasization of pigmented and non-pigmented skin neoplasms.
9. Malignant neoplasms metastasizing the skin.
10. Cutaneous neurofibroma: characteristics and relationships with neurofibromatosis.
11. Sporadic Kaposi's sarcoma and associated with immunodeficiency syndrome.
12. Proliferative lesions and vascular malformations.
1. Primary and metastatic benign and malignant neoplasms of the mucous membrane of the oral cavity.
3. Odontoblastic tumors.
4. Non-neoplastic pathology of the parotid and major salivary glands.
5. Primary and secondary benign and malignant neoplastic pathology of the parotid.
Pathology of the nervous system
1. Intracranial hemorrhages: sites, etiological and pathogenic factors, outcomes.
2. Hypoxic-ischemic lesions of the central nervous system: sites, etiological and pathogenetic factors, outcomes.
3. Meningitis and encephalitis: characteristics, etiological agents, complications.
4. Demyelinating diseases.
5. Congenital malformations of the CNS.
6. Primitive and metastatic intracranial neoplasms: histotypes, staging, grading, complications.
7. Benign and malignant neoplasms of the peripheral nervous system.
8. Pathologies of the retina and eye.
1. Primitive and secondary neoplasms of bone and cartilage.
2. Congenital pathologies of the skeleton.
Soft tissue tumors
1. Benign and malignant neoplasms of soft tissues (main histotypes, metastatic pathways, main macro and microscopic general criteria used to define the benign or malignant nature of soft tissue tumors; staging).
Prerequisites for admission
The student must have acquired knowledge of Normal Anatomy and Histology, Human Embriology, Human Physiology, General Pathology and Genetics, to deal with the topics of the course of Pathology.