Experimental Methodologies and Models in Occupational Toxicology
A.Y. 2025/2026
Learning objectives
The course is aimed to provide knowledge on preclinical models for assessing the toxicity of substances as well as on epidemiological studies in the field of toxicology, with a focus on work-related diseases. Additionally, knowledge on the main research methodologies for gathering information and interpreting scientific literature will be provided.
Expected learning outcomes
At the end of the course, the student should acquire: (i) basic skills in designing and interpreting preclinical toxicity studies; (ii) basic skills in designing and interpreting epidemiological studies; (iii) knowledge of current regulations in preclinical and clinical settings; (iv) proficiency in methods for researching scientific information and in critically analyzing evidence; (v) understanding of methods and techniques for collecting data about exposure and outcome, identifying environmental and occupational risks, and potential relationships with other factors (genetic, demographic, socioeconomic, psychological, and cultural) associated with health or disease status.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Course syllabus
Introduction to occupational toxicology; experimental models in toxicology (in vitro and in vivo); analytical methods for the assessment of toxic effects; toxicological and biological risk assessment; case studies in occupational toxicology (e.g., exposure to metals, solvents, and air pollutants), including the analysis of diseases associated with occupational exposure.
Prerequisites for admission
Students are expected to have a basic understanding of general toxicology, as well as a general knowledge of human anatomy, general biology, physiology, and biochemistry.
Teaching methods
Frontal lessons, interactive activities, and group work aimed at discussing, analyzing, and presenting in class the most recent findings from the scientific literature.
Teaching Resources
Course materials will be available on the myAriel platform.
Assessment methods and Criteria
The exam consists of an oral test, during which students may present a brief report on a topic of their choice. The assessment will focus on the student's ability to think critically, to independently elaborate on the chosen topic, and to demonstrate a solid understanding of the concepts covered during the course. The final grade will be expressed on a 30-point scale.
Professor(s)