General Pathology and Physiopathology
A.Y. 2025/2026
Learning objectives
The course aims to provide students with the knowledge underlying diseases, with particular focus on the study of etiology (causes of disease), pathogenesis (mechanisms by which causes act), and the biological bases through which diseases produce specific signs or symptoms. The topics covered will include the nature and causes of cellular damage and death, acute and chronic inflammation and repair mechanisms, physio-pathology of the immune system, neoplasms, diseases related to glucose metabolism, liver diseases, arterial hypertension, thyroid pathologies, and anemias.
Expected learning outcomes
To understand pathological mechanisms related cell injury and death, adaptive cellular changes, apoptosis and necrosis, inflammation, healing and repair, immune system, and neoplasia.
To discriminate etiology and pathological mechanisms related to plant extracts.
Use the terminology for the field of pathology correctly and contextually.
To acquire the ability to relate these essential basic pathological processes to the pathogenesis of common and important diseases, e.g. neoplasia and inflammation
To discriminate etiology and pathological mechanisms related to plant extracts.
Use the terminology for the field of pathology correctly and contextually.
To acquire the ability to relate these essential basic pathological processes to the pathogenesis of common and important diseases, e.g. neoplasia and inflammation
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
Course syllabus
- Etiology and pathogenesis
- Cholera, sickle cell anemia, cystic fibrosis
- Cellular damages
- Atrophy and hypertrophy
- Hyperplasia
- Metaplasia
- Steatosis
- Amyloidosis
- Necrosis and apoptosis
- Neoplasia
- Angiogenesis
- Carcinogenesis
- Prions
- Diabetes (type 1, type 2 and gestational)
- Hepatitis
- Haematopoiesis
- Hypertension
- Immunity (innate and acquired)
- Cholera, sickle cell anemia, cystic fibrosis
- Cellular damages
- Atrophy and hypertrophy
- Hyperplasia
- Metaplasia
- Steatosis
- Amyloidosis
- Necrosis and apoptosis
- Neoplasia
- Angiogenesis
- Carcinogenesis
- Prions
- Diabetes (type 1, type 2 and gestational)
- Hepatitis
- Haematopoiesis
- Hypertension
- Immunity (innate and acquired)
Prerequisites for admission
Physiology: endocrine system, cardiovascular system, lymphatic system.
Anatomy: The liver, the pancreas, the thyroid.
Anatomy: The liver, the pancreas, the thyroid.
Teaching methods
Standard teacher-based lessons.
Teaching Resources
- All the slides are present on the Ariel webpage
- Fabio Celotti, Patologia Generale e Fisiopatologia, II Edizione, Edises, 2013
- Kumar, Robbins Fondamenti di Patologia e di Fisiopatologia, Edra, 2013
- Pontieri, Elementi di Patologia Generale e Fisiopatologia Generale, Piccin, 2012
- Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai: Immunologia cellulare e molecolare. Elsevier Ed
- Fabio Celotti, Patologia Generale e Fisiopatologia, II Edizione, Edises, 2013
- Kumar, Robbins Fondamenti di Patologia e di Fisiopatologia, Edra, 2013
- Pontieri, Elementi di Patologia Generale e Fisiopatologia Generale, Piccin, 2012
- Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai: Immunologia cellulare e molecolare. Elsevier Ed
Assessment methods and Criteria
Oral test to evaluate students' knowledge of the fundamental concepts of the subject. Positive marks range from 18 to 30; e.g., 18/30 (the lowest mark) or 30/ 30 cum laude (the highest mark).
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 6
Lessons: 48 hours
Professor:
Ruscica Massimiliano
Professor(s)