Mendelian genetics, basic knowledge of human genome structure.
Basic mechanism of transcriptional regulation.
Basic knowledge on chromatin structure, the nucleosome and higher-order chromatin structure.
Principles of Epigenetics: basic concepts on DNA methylation, histone post-translational modifications, the histone code hypothesis.
X-chromosome inactivation and imprinting.
Basic knowledge of neuroanatomy and neurophysiology.
Modalità di verifica dell’apprendimento e criteri di valutazione
For the BIO13 module only, learning will be assessed through the presentation of scientific articles in Journal Clubs held by small groups of students during the course and by means of a written examination with open questions at the end of the course. A written examination with open questions at the end of the course will be also applied at the end of the course for learning assessment concerning topics of MED03 module.
- Evaluation parameters will include i) specific knowledge of the subject, ii) familiarity with the relevant literature and ability to critically discuss each topic. In the written test, respect of formal and linguistic issues will be also considered.
- The final mark will be the result of the weighted average of BIO13 and MED03 marks considering 8 cfu for BIO13 and 6 cfu for MED03.
The final mark will be given on a 30 points basis (grades out of thirty) and the minimum passing mark is 18/30.
A positive evaluation for one of the two modules (BIO13 or MED03) will remain valid for the entire current academic year.
Examination results will be published in the Notice Board of the Ariel website.
ATTENDANCE: Attendance is required to be allowed to take the exam.