Advanced course in Biotechnology and Pharmacology

A.Y. 2019/2020
7
Max ECTS
88
Overall hours
SSD
BIO/14
Language
Italian
Learning objectives
1. Fornire lo studente con le competenze necessarie ad affrontare studi di ingegneria cellulare con sistemi reporter per lo studio in vitro della attività di farmaci e composti ad potenziale attività tossica
2. Fornire allo studente le competenze teoriche per studi di tipo genetico volti a migliorare lo studio della attività ed effetti collaterali di nuove molecole a potenziale attività terapeutica.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Lesson period
First semester
Practical course on Biotechnology and Pharmacology
Course syllabus
Briefly, lectures will address:
The evolution of R&D from the '90ties to date
The different phases of preclinical research:
· Innovative target identification
· Drug screening
· ADMET (drug metabolism and toxicology) I contributi delle biotecnologie alla moderna ricerca farmacologica:
Identification of the molecular bases of mono- and poly genic diseases
DNA sequencing and regulation of gene expression
The Human Genome project and its relevance for drug development
'omics and their application in R&D
Bioinformatics in drug discovery
Creation of data banks and their relevance for biological research
Cell and animal engineering
Innovative drug screening
Imaging technologies in drug development
Innovative therapeutic strategies:
· Nucleic acid sas drugs
· Gene therapy
· Cell therapy
Pharmacogenomics
BIO/14 - PHARMACOLOGY - University credits: 3
Single bench laboratory practical: 16 hours
Lessons: 16 hours
Practical course on Biotechnology and Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Single bench laboratory practical: 48 hours
Lessons: 8 hours