Communicable and Non-Communicable Diseases

A.Y. 2020/2021
8
Max ECTS
64
Overall hours
SSD
BIO/19 MED/04
Language
English
Learning objectives
The objective of the course is to provide a specific knowledge and a critical evaluation on the pathological bases for precision medicine interventions. The overall learning objective is thus to provide an updated discussion of selected topics on precision medicine, which is notoriously a present and future important biomedical approach and includes relevant biotechnological aspects. The course includes two modules: Pathological bases for precision medicine interventions and Infectious diseases and drug resistance. In the first module, the following topics will be discussed: general principles of precision medicine, molecular determinants of individual health, precision medicine in oncology (molecular determinants, examples of precision medicine in oncology), precision medicine in cardiovascular and metabolic health, machine learning and artificial intelligence for precision medicine. In the second module, the following topics will be discussed: overview of human-microbe interactions, antimicrobial compounds: mechanism of action and resistance, identifying novel conventional targets for antimicrobial discovery, and non-conventional targets for novel generation of antimicrobial compounds, challenges in novel antimicrobial compound discovery.
Expected learning outcomes
At the end of the course, the students are expected to possess a solid knowledge and understanding on the pathological bases for precision medicine interventions. The acquired skills and competencies will be the tools through which the students will improve their capacity to correlate the different concepts in different areas of precision medicine, applying their skills to the comprehension of complex problems in this field. Moreover, they will be enabled to implement better judgment, communication skills and learning abilities in this complex scientific area, especially in relationship with topics relevant to biotechnology.
Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Course syllabus and organization

Single session

Responsible
Lesson period
First semester
The current COVID-19 pandemic required the prompt adaptation of the teaching activities to an unprecedented setting. The teacher of this course, with the support of UNIMI (see for reference: "Didattica online. Dalla fase 2 al ritorno in aula" (https://work.unimi.it/servizi_insegna/ariel/123737.htm and https://work.unimi.it/servizi_insegna/ariel/119559.htm)), implemented the most effective strategies to overcome the difficulties linked to this situation, in some instances trying to turn a negative condition into a novel opportunity. All the changes listed below are clearly intended to be linked to the contingent emergency situation and, in any case, the maximum effort is done to maintain the best overall quality of the course.
The program of this course is unchanged in terms of topics and number of lessons/hours/credits.
The main modality of lesson release will be directly online (synchronous) at specific times reported on the timetable. The Teams platform will be preferentially used, although other (i.e., Zoom) may work as backups. All synchronous lessons will be also recorded and available on the Ariel platform, along with any additional material. Moreover, some lessons may be delivered only as recorded lectures.
During the emergency time, tests will be conducted online, only orally, using the Teams platform. The positive scores will range from 18/30 to 30/30 with honours.
Course syllabus
The course includes two modules: Pathological bases for precision medicine interventions and Infectious diseases and drug resistance.
In the first module, the following topics will be discussed: general principles of precision medicine, molecular determinants of individual health, precision medicine in oncology (molecular determinants, examples of precision medicine in oncology), precision medicine in cardiovascular and metabolic health, machine learning and artificial intelligence for precision medicine. In the second module, the following topics will be discussed: overview of human-microbe interactions, antimicrobial compounds: mechanism of action and resistance, identifying novel conventional targets for antimicrobial discovery, and non-conventional targets for novel generation of antimicrobial compounds, challenges in novel antimicrobial compounds discovery.
Prerequisites for admission
Basic knowledge of biochemistry, physiology, microbiology, pathology
Teaching methods
Active lectures
Teaching Resources
Selected scientific materials (articles, websites) will be provided.
The lesson slides will be available on the Ariel website to the students.
Assessment methods and Criteria
Oral exam
Infectious diseases and drug resistance
BIO/19 - MICROBIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Lessons: 16 hours
Professor: Polissi Alessandra
Pathological bases for precision medicine interventions
BIO/19 - MICROBIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Lessons: 48 hours
Professor: Magni Paolo
Professor(s)
Reception:
by appointment
Department of Pharmacological and Biomolecular Sciences
Reception:
Upon request
Department of Pharmacological and Biomolecular Sciences - Via Balzaretti 9 - Milano