A.Y. 2021/2022
Overall hours
Learning objectives
General aims of the course: (1) To introduce  students to the molecular design of life, including structural and biological properties of the main constituents of organisms; (2) To describe the molecular basis of the main biological processes, with particular emphasis on the metabolic fate of the lipidic, proteic and glicidic components of food; (3) To detail molecular basis of energy production from the main food components under aerobic and anaerobic conditions; (4) To introduce students to the main molecular biology mechanisms, including DNA replication, RNA and protein synthesis; (5) To detail the structure-function relationship in proteins; (6) To describe the biological roles of vitamins.
Expected learning outcomes
1- Knowledge and understanding. The course is aimed at providing information concerning (a) the structure and function of the most relevant biomolecules, including macromolecules, with particular emphasis on proteins (b) the main biological processes operating in animal cells, including the biological fate of the main components of nutrients, mechanisms of energy production and storage, molecular mechanisms of metabolic control and signal transduction and (c) expression of genetic information.
2-Ability to apply knowledge and understanding. At the end of the course the student must be able to distinguish the main metabolic effects of the proteic, lipidic and glicidic components of food, with particular emphashis on their relative role in energy production and storage under aerobic or anaerobic conditions. Such information is of the utmost importance to understand the metabolic/dismetabolic, physiological/pathological and nutritional processes described in later courses related to animal productions.
Course syllabus and organization

Single session

Lesson period
Second semester
More specific information on the delivery modes of training activities for a.y. 2021-22 will be provided over the coming months, based on the evolution of the public health situation. It is expected to be able to do the lessons in the presence, since the classroom allows to maintain the necessary distance between the students, in compliance with the indications in force. In the event that this is not possible, the lessons will be on Microsoft Teams, recorded and made available to students on the same web platform. Information on the organization of lessons and any other information on teaching will be available on the ARIEL teaching website: it is therefore recommended to consult it regularly. Based on the evolution of the epidemic and in compliance with the relevant regulations, it will be possible to modify the modalities of the activities planned in the classroom, informing the students via ARIEL.
The teaching program and reference material will not be affected. The final test will consist on a multiple choice test by Moodle Proctoring.
Course syllabus
Protein structural levels (2 hours)
Collagen (2 hours)
Membranes and membrane transport(2 hours)
Myoglobin and hemoglobin (2 hours)
Enzymes, mechanism and regulation of enzyme action. Zymogen (2 hours)
Molecular mechanism of digestion, absorption and transport of biomolecules (2 hours)
Metabolism and bioenergetics(2 hours)
Carbohydrates metabolism: glycolysis, pentose phosphate pathway, glycogen, gluconeogenesis, synthesis of lactose (4 hours)
TCA cycle and oxidative phosphorylation (2 hours)
Fatty acid catabolism and lipid biosynthesis. Ketone bodies. Cholesterol metabolism (4 hours)
Amino acid metabolism, ammonia metabolism and urea cycle (2 hours)
Nucleotides: purinies and pyrimidines metabolism (2 hours)
Metabolic integration and intra-extra cellular regulation (2 hours)
Nucleic acids and biological function. Genetic code. DNA replication, transcription, gene expression and protein synthesis (10 hours)
Rumen biochemistry (6 hours)
Lab techologies (2 hours)
Prerequisites for admission
Good basic knowledge of organic chemistry is recommended.
Teaching methods
6 CFU (48 hours) lectures
Teaching Resources
Campbell/Farrell: BIOCHIMICA (EdiSES)
Educational material available on the Ariel teaching platform
Assessment methods and Criteria
The final test consists of a written exam with 5 questions concerning the various topics of the program. It will be assessed in thirtieths and the final grade will take into account the accuracy and quality of the answers, as well as the proper use of the specific language of the discipline.
BIO/10 - BIOCHEMISTRY - University credits: 6
Lessons: 48 hours
Professor: Nonnis Simona
Monday 12.30-13.30
Department of Veterinary Medicine, Via dell'Università, 6 - 26900 Lodi, Italy