Molecular and Cellular Bases of Metabolic and Nutritional Diseases
A.Y. 2023/2024
Learning objectives
The aim of the course is to provide the bases for the understanding of metabolic and nutrition disorders by discussing the molecular and cellular mechanisms behind such human diseases. By the end of the course, students will have an overview of the correlations that exist between molecular/cellular disfunctions and the macroscopic phenotype of the disease. Moreover, students will be able to critically evaluate and discuss the latest scientific literature focused on metabolic and nutrition disorders.
Expected learning outcomes
At the end of the course, students should have acquired a comprehensive view of the interrelations between molecular and cellular malfunctions and the macroscopic phenotype of the disease. Moreover, students should have developed the ability to understand, interpret and critically evaluate the scientific literature in the field e to disseminate the conclusions emerging from such publications.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Course syllabus
Adverse reaction to Foods: food allergy, coeliac disease, food intolerance, and toxic reaction.
Malabsorption Syndromes.
Nutritional disorders: malnutrition (undernutrition and overnutrition).
Metabolic alterations: metabolic syndrome.
Gastrointestinal pathologies: irritable bowel syndrome, Crohn's disease, ulcerative colitis.
Metabolic and nutritional disorders and cardiovascular pathology: atherosclerosis and hypertension.
Metabolic and nutritional disorders and liver pathology: cirrhosis, steatosis.
Metabolic and nutritional disorders and kidney pathology: chronic kidney disease.
Metabolic and nutritional disorders: cancer cachexia
Malabsorption Syndromes.
Nutritional disorders: malnutrition (undernutrition and overnutrition).
Metabolic alterations: metabolic syndrome.
Gastrointestinal pathologies: irritable bowel syndrome, Crohn's disease, ulcerative colitis.
Metabolic and nutritional disorders and cardiovascular pathology: atherosclerosis and hypertension.
Metabolic and nutritional disorders and liver pathology: cirrhosis, steatosis.
Metabolic and nutritional disorders and kidney pathology: chronic kidney disease.
Metabolic and nutritional disorders: cancer cachexia
Prerequisites for admission
Students must know basic concepts of general physiology and biochemistry
Teaching methods
Teaching will be based on interactive frontal lectures supported by projected slides. Students will be actively involved into discussions to elaborate the topics covered during the lectures with a critical point of view, in order to improve their independent thinking and communication skills.
Attendance to the course is strongly recommended
Attendance to the course is strongly recommended
Teaching Resources
The course is entirely based on bibliographic material. Lecture slides, scientific research articles and reviews regarding each lecture topics (uploaded on ARIEL)
Assessment methods and Criteria
The final exam consists of:
a) Oral presentation and discussion of of scientific article in front of their classmates (max 3/30)
b) a written essay composed of 2 open questions on the topics covered during the course(max 27/30)
The final mark will be the sum of the written essay and the article presentation/discussion.
The evaluation takes into account the ability of the student to handle the topics covered by the course and to use proper scientific communication skills.
The exam result will be communicated by e-mail.
a) Oral presentation and discussion of of scientific article in front of their classmates (max 3/30)
b) a written essay composed of 2 open questions on the topics covered during the course(max 27/30)
The final mark will be the sum of the written essay and the article presentation/discussion.
The evaluation takes into account the ability of the student to handle the topics covered by the course and to use proper scientific communication skills.
The exam result will be communicated by e-mail.
BIO/09 - PHYSIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Lessons: 48 hours
Professors:
Bucchi Annalisa, Fantin Alessandro
Educational website(s)
Professor(s)
Reception:
on request, via email
via G. Celoria, 26 20133 Milano, B tower, 6th floor