Medicinal Chemistry 1

The lectures are aimed at providing the student with background knowledge and understating
- of how drugs interacts with their biological targets
- of how drugs get to their targets (ADMET)
- of the main principles of drug design and development
- of the issues in drug design (SAR and QSAR)
- of some classes of drugs, such as antibacterial, antiprotozoal, antiviral and anticancer agents.

At the end of the course, the student is expected:
- to know the principles and the strategies applied in the rational drug design;
- to critically evaluate the chemico-physical properties and the structure-activity relationships for the considered classes of drugs
- to gain the theoretical bases to understand how the pharmacokinetic profile influences the activity of a given drug
- to reach lifelong learning skills involving a multifaceted knowledgebase on how the chemical properties impact on drug activity. These skills will be useful for further student's personal study and will allow a proper evaluation of the new drugs that will reach the market.