Fundamental definitions and concepts in Analytical Chemistry; Elements of statistics applied to analytical chemistry; interpretation of acid/base, precipitation, complexation and redox equilibria, with application to volumetric analysis; electroanalysis fundamentals: conductimetry, potentiometry, voltammetry, amperometry
Applying basic statistics to estimate reliability and significance of analytical data, also in connection with the laboratory module.
Managing solution equilibria and electrode potentials, also in terms of ionic activities, and application for prediction and interpretation of titration curves based on acid/base, precipitation, complexation and redox equilibria, with full instrumental monitoring or end point detection by colorimetric indicators, also in connection with the laboratory module.
Basic knowledge of fundamental electroanalytic techniques (conductimetry, potentiometry, voltammetry, amperometry) also in connection with the laboratory module.
Course content [required]
Part 1 Propedaeutic concepts Analytical Chemistry: definition, history, significance. Analytical methods. Sequence of steps in a typical quantitative analysis. Sampling (hints). Elements of theory of errors applied to analytical chemistry; criteria for data treatment and statistical tests. Concentration scales, ionic strength, activities, activity coefficients. Equilibrium constants, standard states. Nernst law, galvanic cells, ion-reversible electrodes, electrode potential scale.
Part 2 Equilibria in solution and volumetric analysis. Titration methods: definitions, classification, standards. Acid/base, precipitation, complessation and redox titrations: mathematical description of the corresponding equilibria and elaboration and interpretation of titration diagrams for model systems. Speciation diagrams and Pourbaix diagrams.
Part 3 Electroanalysis. Conductimetry, potentiometry (ion-selective electrodes, pH-metry, p-Ionometry, redox potential, water hardness), voltammetry (cyclic voltammetry, polarography, pulsed techniques, stripping techniques for trace analysis), amperometry (trace water by Karl Fischer method, dissolved oxygen by Clark method), biosensors and electronic tongues/noses (hints). Fundamentals, instrumentation, protocols (standardization, direct measurements, instrumental titrations). Model cases in the analytical laboratory and in fundamental and applied research.
General and Inorganic Chemistry and General and Inorganic Chemistry Laboratory; Mathematics courses.
Recommended general scope textbook: Douglas A. Skoog, Donald M. West, F. James Holler, Fundamentals of Analytical Chemistry, Brooks Cole (or corresponding Italian edition)
Supporting material and model electronic spreadsheets provided by the instructor (available on her website under password)
Other general scope textbook: Daniel C. Harris, Quantitative Chemical Analysis, W.H. Freeman & Co. (or corresponding Italian edition)
For a deeper insight and attractive treatment of acid base equilibria and corresponding titration curve: Robert De Levie, Aqueous Acid-Base Equilibria and Titrations, Oxford Chemistry Primers.
Fundamentals of General and Inorganic Chemistry; basic stoichiometric calculations: elements of mathematical analysis and of numerical methods.
The global mark of the Analytical Chemistry and Laboratory of Analytical Chemistry I Course will be assigned combining the marks obtained for the theoretical and experimental modules (details concerning the latter evaluation are provided in the corresponding
Concerning the evaluation of the theoretical module, it will consist in
A 3-hour written examination concerning the program Part 1 and 2 (mainly problems and exercises, plus several short questions)
A 15-minutes oral examination concening the program Part 3 (electroanalytical techniques). Students can register for this interview, enabling them to complete the examination and to receive their global mark for the entire course, after having passed both the above written examination and the laboratory module examination.
Language of instruction
Attendance is strongly recommended
Mode of teaching: