Analytical Chemistry with Lab
A.Y. 2019/2020
Learning objectives
Aim of this course is to approach the basics of classical Analytical Chemistry.
Expected learning outcomes
The student will be able to know the principles of classical analytical chemistry and to evaluate their applications.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Prerequisites for admission
General and Inorganic Chemistry and General and Inorganic Chemistry Laboratory; Mathematics courses.
Assessment methods and Criteria
The global mark of the Course will be assigned combining the marks obtained for the theoretical and experimental parts.
Concerning the evaluation of the theoretical part, it will consist in:
- a 3-hour written examination concerning the program Part 1 and 2 (mainly problems and exercises, plus several short questions);
- a 15-minutes oral examination concening the program Part 3 (electroanalytical techniques). Students can register for this interview, enabling them to complete the examination and to receive their global mark for the entire course, after having passed both the above written examination and the laboratory part examination.
Concerning the evaluation of the laboratory part, it will consist in:
- written examination (2 hours) based on 5 open questions. In particular: 2 excercises of stoichiometric/analytical calculations; 1 question related to the laboratory protocols; 1 question on the theoretical part of the course and 1 question on the Quality Control part.
The behaviour in the Laboratory, the Laboratory Diary and the Reports on the Laboratory experiments and on the Quality Control will be also evaluated in itinere.
Concerning the evaluation of the theoretical part, it will consist in:
- a 3-hour written examination concerning the program Part 1 and 2 (mainly problems and exercises, plus several short questions);
- a 15-minutes oral examination concening the program Part 3 (electroanalytical techniques). Students can register for this interview, enabling them to complete the examination and to receive their global mark for the entire course, after having passed both the above written examination and the laboratory part examination.
Concerning the evaluation of the laboratory part, it will consist in:
- written examination (2 hours) based on 5 open questions. In particular: 2 excercises of stoichiometric/analytical calculations; 1 question related to the laboratory protocols; 1 question on the theoretical part of the course and 1 question on the Quality Control part.
The behaviour in the Laboratory, the Laboratory Diary and the Reports on the Laboratory experiments and on the Quality Control will be also evaluated in itinere.
Analytic chemistry
Course syllabus
Part 1 Propedaeutic concepts Analytical Chemistry: definition, history, significance. Analytical methods. Sequence of steps in a typical quantitative analysis. Sampling (hints). Elements of theory of errors applied to analytical chemistry; criteria for data treatment and statistical tests. Concentration scales, ionic strength, activities, activity coefficients. Equilibrium constants, standard states. Nernst law, galvanic cells, ion-reversible electrodes, electrode potential scale.
Part 2 Equilibria in solution and volumetric analysis. Titration methods: definitions, classification, standards. Acid/base, precipitation, complessation and redox titrations: mathematical description of the corresponding equilibria and elaboration and interpretation of titration diagrams for model systems. Speciation diagrams and Pourbaix diagrams.
Part 3 Electroanalysis. Conductimetry, potentiometry (ion-selective electrodes, pH-metry, p-Ionometry, redox potential, water hardness), voltammetry (cyclic voltammetry, polarography, pulsed techniques, stripping techniques for trace analysis), amperometry (trace water by Karl Fischer method, dissolved oxygen by Clark method), biosensors and electronic tongues/noses (hints). Fundamentals, instrumentation, protocols (standardization, direct measurements, instrumental titrations). Model cases in the analytical laboratory and in fundamental and applied research.
Part 2 Equilibria in solution and volumetric analysis. Titration methods: definitions, classification, standards. Acid/base, precipitation, complessation and redox titrations: mathematical description of the corresponding equilibria and elaboration and interpretation of titration diagrams for model systems. Speciation diagrams and Pourbaix diagrams.
Part 3 Electroanalysis. Conductimetry, potentiometry (ion-selective electrodes, pH-metry, p-Ionometry, redox potential, water hardness), voltammetry (cyclic voltammetry, polarography, pulsed techniques, stripping techniques for trace analysis), amperometry (trace water by Karl Fischer method, dissolved oxygen by Clark method), biosensors and electronic tongues/noses (hints). Fundamentals, instrumentation, protocols (standardization, direct measurements, instrumental titrations). Model cases in the analytical laboratory and in fundamental and applied research.
Teaching methods
Frontal traditional lessons.
Teaching Resources
Testo raccomandato:
- Douglas A. Skoog, Donald M. West, F. James Holler, Fundamentals of Analytical Chemistry, Brooks Cole (o l'edizione corrispondente italiana)
- Materiale integrativo e fogli elettronici modello forniti dal docente (scaricabili dal sito con password)
Altro testo di carattere generale:
-Daniel C. Harris, Quantitative Chemical Analysis, W.H. Freeman & Co. (o l'edizione corrispondente italiana).
Per un approfondimento degli equilibri acido/base e della costruzione delle corrispondenti curve di titolazione:
- Robert De Levie Aqueous Acid-Base Equilibria and Titrations, Oxford Chemistry Primers.
- Douglas A. Skoog, Donald M. West, F. James Holler, Fundamentals of Analytical Chemistry, Brooks Cole (o l'edizione corrispondente italiana)
- Materiale integrativo e fogli elettronici modello forniti dal docente (scaricabili dal sito con password)
Altro testo di carattere generale:
-Daniel C. Harris, Quantitative Chemical Analysis, W.H. Freeman & Co. (o l'edizione corrispondente italiana).
Per un approfondimento degli equilibri acido/base e della costruzione delle corrispondenti curve di titolazione:
- Robert De Levie Aqueous Acid-Base Equilibria and Titrations, Oxford Chemistry Primers.
Laboratory of analytic chemistry
Course syllabus
Lessons first part [16 hours] Concentration and concentration scales. Dilutions. Laboratory materials and reagents. Instrumentation for mass and volume measurements. Analytical methods characteristics, prediction and analysis methodologies. Safety regulations. Good laboratory practice. General principles of acid-base, precipitation, complexometric and redox titrations. General principles of conductimetry, potentiometry and pH-metry, amperometry. Survey of experimental procedures.
Lessons second part [12 hours]
Quality control of the chemical products and processes. The seven basic tools: Flow charts, Control charts, Scatter diagrams, Cause-and-effect diagrams (Ishikawa), Pareto charts, Histograms, Check sheets. Hints about the Quality Control ISO 9001 Norm.
Numerical exercises first part [8 hours] Calculations concerning solution preparation and titrations. Excel electronic spreadsheet use for experimental data treatment.
Numerical exercises second part [8 hours]
Excel electronic spreadsheet use for the preparation and implementation of the quality control tools.
Laboratory experiments [20 hours]
1) precipi¬tation titrations (determination of chlorides with Mohr, Fajans and potentiometric methods);
2) complexation titrations (colorimetric and potentiometric determination of water hardness with EDTA);
3) redox titrations (iodometric determination of ascorbic acid with colorimetric and amperometric methods);
4) Conductimetry: conductimeter calibration, direct measurement of specific con-ducti¬vi¬ty, conductimetric titrations;
5) pH-metry: pH-meter standardization and direct pH measurements; colorimetric and potentiometric acid/base (HCl, HCl+CH3COOH) titrations.
Lessons second part [12 hours]
Quality control of the chemical products and processes. The seven basic tools: Flow charts, Control charts, Scatter diagrams, Cause-and-effect diagrams (Ishikawa), Pareto charts, Histograms, Check sheets. Hints about the Quality Control ISO 9001 Norm.
Numerical exercises first part [8 hours] Calculations concerning solution preparation and titrations. Excel electronic spreadsheet use for experimental data treatment.
Numerical exercises second part [8 hours]
Excel electronic spreadsheet use for the preparation and implementation of the quality control tools.
Laboratory experiments [20 hours]
1) precipi¬tation titrations (determination of chlorides with Mohr, Fajans and potentiometric methods);
2) complexation titrations (colorimetric and potentiometric determination of water hardness with EDTA);
3) redox titrations (iodometric determination of ascorbic acid with colorimetric and amperometric methods);
4) Conductimetry: conductimeter calibration, direct measurement of specific con-ducti¬vi¬ty, conductimetric titrations;
5) pH-metry: pH-meter standardization and direct pH measurements; colorimetric and potentiometric acid/base (HCl, HCl+CH3COOH) titrations.
Teaching methods
Traditional frontal lesson (theory). Single-bench and/or group laboratory experiments. Excercises in Computer-classroom.
Teaching Resources
Lessons Power Point presentations, model electronic spreadsheets, solved exercises, laboratory experimental procedures. All this material is available and downloadable from the instructors' web site.
Recommended text: Douglas A. Skoog, Donald M. West, F. James Holler, Fundamentals of Analytical Chemistry, Brooks Cole.
Kaoru Ishikawa, Guide to Quality Control, Asian Productivity Organization.
Recommended text: Douglas A. Skoog, Donald M. West, F. James Holler, Fundamentals of Analytical Chemistry, Brooks Cole.
Kaoru Ishikawa, Guide to Quality Control, Asian Productivity Organization.
Analytic chemistry
CHIM/01 - ANALYTICAL CHEMISTRY - University credits: 6
Lessons: 48 hours
Professor:
Mussini Patrizia Romana
Shifts:
-
Professor:
Mussini Patrizia Romana
Laboratory of analytic chemistry
CHIM/01 - ANALYTICAL CHEMISTRY - University credits: 6
Practicals: 12 hours
Laboratories: 20 hours
Lessons: 32 hours
Laboratories: 20 hours
Lessons: 32 hours
Shifts:
Corso A
Professor:
Falciola LuigiCorso B
Professor:
Pifferi ValentinaProfessor(s)
Reception:
Every Day from Monday to Friday, 9-18, by appointment
by Professor's Office in via Golgi 19, Building 5A, West Wing (Electrochemistry), III floor, room 3114-O
Reception:
From Monday to Friday, between 8.30 and 18.30, by appointment (to be requested by email))
In my office (Chemistry Department, West Wing, First Floor), or on the Teams platform in videoconference mode.
Reception:
Monday-Friday 9-17, by appointment
Office, via Golgi 19, Edificio 5, Corpo A, III floor, room 3113-O