Molecular and Cellular Bases of Metabolic and Nutritional Diseases
A.Y. 2019/2020
Learning objectives
The aim of the course is to provide the bases for the understanding of metabolic and nutrition disorders by discussing the molecular and cellular mechanisms behind such human diseases. By the end of the course, students will have an overview of the correlations that exist between molecular/cellular disfunctions and the macroscopic phenotype of the disease. Moreover, students will be able to critically evaluate and discuss the latest scientific literature focused on metabolic and nutrition disorders.
Expected learning outcomes
At the end of the course, students should have acquired a comprehensive view of the interrelations between molecular and cellular malfunctions and the macroscopic phenotype of the disease. Moreover, students should have developed the ability to understand, interpret and critically evaluate the scientific literature in the field e to disseminate the conclusions emerging from such publications.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Course syllabus
Nutritional disorders: malnutrition, obesity, anorexia, vitamins
Metabolic alterations: diabetes, gout, metabolic syndrome
Alterations of the hydro-electrolytic balance including calcium metabolism and skeletal pathologies
Gastrointestinal pathologies: coeliac disease, Helicobacter pylori, gastric and duodenal ulcer, Irritable bowel syndrome, Crohn's disease, ulcerative colitis
Adverse reactions to food and food intolerance
Metabolic and nutritional disorders and cardiovascular pathology: atherosclerosis and hypertension
Metabolic and nutritional disorders and kidney pathology: kidney stone pathology
Metabolic and nutritional disorders and liver pathology: cirrhosis, steatosis
Nutrition/obesity and cancer
Metabolic alterations: diabetes, gout, metabolic syndrome
Alterations of the hydro-electrolytic balance including calcium metabolism and skeletal pathologies
Gastrointestinal pathologies: coeliac disease, Helicobacter pylori, gastric and duodenal ulcer, Irritable bowel syndrome, Crohn's disease, ulcerative colitis
Adverse reactions to food and food intolerance
Metabolic and nutritional disorders and cardiovascular pathology: atherosclerosis and hypertension
Metabolic and nutritional disorders and kidney pathology: kidney stone pathology
Metabolic and nutritional disorders and liver pathology: cirrhosis, steatosis
Nutrition/obesity and cancer
Prerequisites for admission
Students must know basic concepts of general physiology and biochemistry
Teaching methods
Teaching will be based on interactive frontal lectures supported by projected slides. Students will be actively involved into discussions to elaborate the topics covered during the lectures with a critical point of view, in order to improve their independent thinking and communication skills.
Teaching Resources
The course is entirely based on bibliographic material. Lecture slides, scientific research articles and reviews regarding each lecture topics (uploaded on ARIEL)
Assessment methods and Criteria
Students knowledge will be assessed with a written essay composed of 2 open questions on the topics covered during the course. Students will also present and discuss a scientific article in front of their classmates. The overall evaluation of the course will take into account both the written essay and the article presentation. The final mark will be the sum of the written essay (max 28/30) and the article presentation (max 2/30).
If the overall examination appears of excellent level, a "cum Laude" will be added to the final mark.
If the overall examination appears of excellent level, a "cum Laude" will be added to the final mark.
BIO/09 - PHYSIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Lessons: 48 hours
Professors:
Bucchi Annalisa, Fantin Alessandro
Shifts:
Professor(s)
Reception:
upon appointment (e-mail)
via G. Geloria 26, Milano 6th floor Tower A
Reception:
on request, via email
via G. Celoria, 26 20133 Milano, B tower, 6th floor