Pharmacology And Toxicology

A.Y. 2019/2020
6
Max ECTS
60
Overall hours
SSD
BIO/14 CHIM/09 MED/43 MED/44 MED/50
Language
Italian
Learning objectives
- knowledge of the chemical groups, toxicants and drugs of abuse, their main mechanisms of action, therapeutic uses , toxic side effects;
- bsic knowledge of toxicology of chemical, physical and biological pollutants in the environment and in the work-place;
- knowledge of the main biochemical and toxicological interactions of drugs, drugs of abuse, enironmental and work-place pollutants;
- knowledge of systems and methods for control of substances of abuse, their main mechanisms of action, terapeutic uses, adverse effects;
- Basic knowledge of formulation, preparation and control of cosmetic products, and current legislation;
- basic knowledge of pharmaco-epidemiology;
Expected learning outcomes
- Knowledge of the fundaments of pharmacology (pharmacokinetics, pharmacodynamics, interactions);
- Knowledge of the fundaments of toxicology;
- Understanding of the meaning of exposure limits and substance classification, and critical application;
- Understanding of the legal framework for the different categories of substances in the environment and work-place, and of the substances of abuse;
- Development of critical skills for the evaluation of exposure to chemicals, their monitoring and control;
- Knowledge of the fundaments on cosmetics, their production, including the GMP, pre- and post-marketing control, and safety issues provided by the EU Regulation 1223/2009.
Course syllabus and organization

Single session

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The examination includes a written part, with open and multiple choice questions, and an oral part. Grades are based on the number of correct answers (multiple choice questions), completeness (open questions and oral exam) and clarity (oral exam) of the answers. The grade is registered and communicated to the student who can either accept or refuse it.
Farmaceutico tecnologico applicato
Course syllabus
1. Composition of cosmetics
2. Manufacture of cosmetics
3. Legislation on cosmetics
Teaching methods
Teaching classes
Teaching Resources
Materiale preparato dai docenti per le lezioni.
Farmacologia
Course syllabus
1. Introduction to pharmacology, mode of action of drugs
2. Pharmacokinetics and dynamics
3. Dose-response of drugs
4. Fate of drugs
5. Routes of administration, including ophthalmic use
6. Absorption, transport mechanisms
7. Biotransformation
8. Distribution
9. Elimination of drugs
10. Response variability
11. Pharmacological interactions and with herbal drugs
12. Genetic basis of response variability
13. Adverse drug reactions
Teaching methods
Teaching classes
Teaching Resources
Materiale preparato dai docenti per le lezioni.
Medicina legale
Course syllabus
1. Introduction to Forensic Medicine
2. Principles of Forensic Medicine
3. Relevant analytical techniques and their use in forensic medicine
4. Biological matrices of toxicological relevance
5. Legislation on drugs and drugs of abuse
6. Principles of forensic histopathology
Teaching methods
Teaching classes
Teaching Resources
Bertol, Lodi, Mari, Marozzi. Trattato di tossicologia forense, CEDAM
Cazzaniga, Cattabeni, Luvoni, Zoja, Compendio di Medicina Legale, UTET (capitoli XVII e XVIII)
Medicina del lavoro
Course syllabus
1. Introduction to toxicology and examples of poisoning at work
2. Poisonings in the living environment, and WHO estimates of deaths attributed to environmental causes.
3. Toxicodynamics and toxicokinetics
4. Principles of industrial hygiene and biological monitoring
5. Introduction to risk assessment
6. Pesticides
7. Molecular mode of action of environmental and occupational contaminants
Teaching methods
Teaching classes
Teaching Resources
Alessio/Apostoli. Manuale di Medicina del lavoro e igiene industriale per tecnici della prevenzione. Piccin (capp. 6, 8, 9, 10).
Auxilia F, Pontello M, Igiene e Sanità Pubblica: Salute e ambiente, a cura di Bertazzi PA e Graspassonni I. PICCIN editore, Capitoli 2, 3 e 4.
Scienze tecniche mediche applicate
Course syllabus
1. Introduction to toxicology and examples of poisoning at work
2. Poisonings in the living environment, and WHO estimates of deaths attributed to environmental causes.
3. Toxicodynamics and toxicokinetics
4. Principles of industrial hygiene and biological monitoring
5. Introduction to risk assessment
6. Pesticides
7. Molecular mode of action of environmental and occupational contaminants
Teaching methods
Teaching classes
Teaching Resources
Materiale preparato dai docenti per le lezioni.
Farmaceutico tecnologico applicato
CHIM/09 - PHARMACEUTICAL AND TECHNOLOGICAL APPLICATIONS OF CHEMISTRY - University credits: 2
Lessons: 20 hours
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 1
Lessons: 10 hours
Professor: Antonucci Flavia
Medicina del lavoro
MED/44 - OCCUPATIONAL MEDICINE - University credits: 1
Lessons: 10 hours
Professor: Fustinoni Silvia
Medicina legale
MED/43 - FORENSIC MEDICINE - University credits: 1
Lessons: 10 hours
Professor: Zoia Riccardo
Scienze tecniche mediche applicate
MED/50 - APPLIED MEDICAL TECHNOLOGY AND METHODOLOGY - University credits: 1
Lessons: 10 hours
Professors: Bollati Valentina, Moretto Angelo