Systems and Diseases Ii

A.Y. 2020/2021
20
Max ECTS
252
Overall hours
SSD
MED/03 MED/08 MED/09 MED/12 MED/13 MED/15 MED/16 MED/18
Language
Italian
Learning objectives
The course represents the synthesis of the notions acquired during the first 3 years and the basis for the subsequent detailed clinical studies the will be carried out during Medical and Specialized Clinics.
The objects are the following:
-to provide the student with the knowledge on the main diseases of Gastrointestinal, Endocrinological, Emathological and Immunoreumathological systems (in particular, etiology, pathophysiology and clinical manifestations)
-to give the main information on the genetics and pathological basis of the above-mentioned diseases
-to provide students with the preparatory tools (language, case history, medical examination) for a correct approach to the patient
-to provide with the main clinical, biochemical, instrumental investigations available to perform a correct diagnosis
Expected learning outcomes
1)To know the pathophysiology of:
DIGESTIVE TRACT
Dysphagia, Dyspepsia, gastroesophageal reflux, chronic gastritis, ulcer
Abdominal distension, Gas, digestion problems, Malabsorption
Intestinale obstruction
Abdominal pain
Jaundice
Hepatic insufficiency, viral and toxic hepatitis, liver diseases such as hemochromatosis and Wilson disease, sclerosant cholangitis
Hepatic encephalopathy
Portal hypertension
Biliary lithiasis
Ascites
Constipation
Diarrhea
Gastrointestinal bleeding
Chronic inflammatory bowel diseases (Crohn disease and ulcerative rectocolitis).

ENDOCRINE - METABOLIC SYSTEM:
Feed-back mechanism and interaction with the other systems
Circadian rithms of hormone secretion. Hormones mechanisms of action
Pathogenetic mechanisms of endocrine disorders and of metabolic diseases: eccess and deficiency
Hormone resistance, bioactivity, alterations of hormone peripheral metabolism
Diseases of thyroid, parathyroids, adrenals, gonads, hypothalamus and pituirary
Metabolic syndrome, insulin resistance
Diabetes type 1&2, gestational diabetes, obesity, hyperuricemia
Monogenic diabetes and obesity
Diabetes complications
Bone metabolism and osteoporosis
Hormones and nutrition

BLOOD:
Differentiation and maturation of blood cells
Role of growth factors
Pathophysiology of the main diseases of blood and lymphohemopoietic organs
Lymphoproliferative and Mieloproliferative diseases
Polycythemia vera and secondary polycythemia
Essential thrombocythemia

IMMUNE SYSTEM:
1) Approach to immunodeficiencies
Approach to autoimmune diseases
Approach to allergic diseases, asthma, rhinitis
Rheumatoid arthritis, Sclerodernia, Sjogren disease
Pathophysiology of joints diseases
Pain in rheumatic diseases
Mineral and uric acid metabolism

2) To know how to define a disease, its epidemiology, etiology and pathophysiology, nosography, signs and symptoms; to interpret the pathophysiological causes of signs and symptoms, the biochemical data, the instrumental investigations. The genetics and pathological basis is also requested for certain diseases.

3) To know the indications and limitations of the main diagnostic approaches
Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Course syllabus and organization

Linea: Policlinico

Responsible
Modules or teaching units
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours

Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Shifts:
Gruppo 1
Professor: Mantovani Giovanna
Gruppo 2
Professor: Mantovani Giovanna
Gruppo 3
Professor: Arosio Maura
Gruppo 4
Professor: Giavoli Claudia

Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Shifts:
Professors: Lampertico Pietro, Penagini Roberto, Tontini Gian Eugenio, Vecchi Maurizio
Gruppo 1
Professor: Vecchi Maurizio
Gruppo 2
Professor: Lampertico Pietro
Gruppo 4
Professor: Penagini Roberto

General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours
Professors: Botti Fiorenzo, Carrara Alberto, Rossi Giorgio Ettore

Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours

Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 1
Lessons: 12 hours
Professor: Miozzo Monica Rosa

Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours

Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Lessons: 36 hours
Professor: Cimaz Rolando

Linea: San Donato

Responsible
Modules or teaching units
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professors: Finazzi Maria Chiara, Rambaldi Alessandro

Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours

Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professor: Pastorelli Luca

General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours

Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours
Professor: Froldi Marco

Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 1
Lessons: 12 hours
Professor: Ghezzi Daniele

Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours
Professor: Pruneri Giancarlo

Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Lessons: 36 hours

Linea: San Giuseppe

Responsible
Modules or teaching units
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professors: Baldini Luca, Fattizzo Bruno, Neri Antonino, Onida Francesco

Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours

Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professors: Penagini Roberto, Rumi Mariagrazia

General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours
Professor: Favi Evaldo

Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours

Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 1
Lessons: 12 hours

Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours
Professor: Pelosi Giuseppe

Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Lessons: 36 hours

Professor(s)
Reception:
by appointment via email
Fondazione IRCCS Ospedale Maggiore Policlinico, building ZONDA , via Lamarmora 5
Reception:
Thursday 12.00 am - 01.00 pm
IRCCS Istituto Auxologico, via Ariosto 9, Milan
Reception:
14.00-15.00
Studio Medici U.O.C. Trapianti di Rene - Padiglione Croff - Ospedale Maggiore Policlinico
Reception:
by telephone appointment
via L. Temolo 4, 20126 Milano - Lab of Neurogenetics and mitochondrial disorders
Reception:
To be arranged by e-mail
Hematology, Fatebenefratelli Hospital, Via Castelfidardo n.15, 20121 Milano
Reception:
Send an e-mail to schedule an appointment
San Paolo Hospital - Block A, Third floor, room 38 - Via Di Rudinì 8, Milan
Reception:
Monday 12.00-13.00 (by appointment)
Interhospital Pathology Division, Science and Technology Park, Via Fantoli 16/15, 20138 Milano
Reception:
Available on request
RCCS Ca' Granda - Ospedale Maggiore Policlinico - Pad. Invernizzi - 5th floor, wing B