Medicine and Pharmacology
A.Y. 2023/2024
Learning objectives
To Know the principles of pharmacodynamics, pharmacokinetics and the main drug interactions.
To Know the relevant human pathologies in the internal medicine field and their therapeutic approach.
To Know the mechanisms of action and the side effects of the main classes of drugs.
To Know the mechanisms of action and the effects of the substances of abuse.
To Know the concept of pharmacovigilance.
To Know the relevant human pathologies in the internal medicine field and their therapeutic approach.
To Know the mechanisms of action and the side effects of the main classes of drugs.
To Know the mechanisms of action and the effects of the substances of abuse.
To Know the concept of pharmacovigilance.
Expected learning outcomes
The student will describe the etiopathogenetic and pathophysiological mechanisms of diseases relevant to Internal Medicine, the signs and symptoms of presentation, the diagnostic and therapeutic indications and the relative urgency, and the differential diagnosis through an inductive-deductive process that begins from presenting symptoms and signs of disease.
It will list and describe the main classes of drugs and their active ingredients.
It will describe the indication, the expected effect, the undesirable effects and the interactions of the active components.
Describe the mechanisms of action and the effects of substances of abuse.
It will explain the mechanisms of pharmacodynamics and pharmacokinetics, in particular the mechanisms of action of drugs, of the factors that influence the absorption, distribution, metabolism and excretion of drugs.
It will explain the concept of pharmacovigilance and pharmacogenetics.
It will list and describe the main classes of drugs and their active ingredients.
It will describe the indication, the expected effect, the undesirable effects and the interactions of the active components.
Describe the mechanisms of action and the effects of substances of abuse.
It will explain the mechanisms of pharmacodynamics and pharmacokinetics, in particular the mechanisms of action of drugs, of the factors that influence the absorption, distribution, metabolism and excretion of drugs.
It will explain the concept of pharmacovigilance and pharmacogenetics.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Sezione: Cesano Boscone
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
2. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
8. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
9. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
10. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
11. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
12. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
13. Drugs used to regulate fertility
14. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
15. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
11. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
16. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
2. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
8. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
9. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
10. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
11. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
12. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
13. Drugs used to regulate fertility
14. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
15. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
11. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
16. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova: Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Milano: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Milano: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
3. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
4. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
5. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
-
6. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
1. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
2. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
3. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
4. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
5. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
6. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
7. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
Urinary tract infections
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
3. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
4. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
5. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
-
6. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
1. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
2. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
3. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
4. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
5. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
6. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
7. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
Urinary tract infections
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova: Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Milano: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Milano: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
Beretta Mauro, Giardini Gianluca Vittorio
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Cella Silvano Gabriele
Sezione: Fondazione Don Gnocchi
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1
and Internship 1.
and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic,
language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic,
language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and
signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of
therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and
signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of
therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli
editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed).
Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli
editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed).
Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli
editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed).
Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli
editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed).
Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Antonucci Flavia, Bifari Francesco
Sezione: Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Rigamonti Antonello Emilio
Sezione: IRCCS Policlinico San Donato
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
Gualtierotti Roberta, Lombardi Rosa
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Bordignon Susanna
Sezione: Istituto Nazionale dei Tumori
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana).Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Cattaneo Maria Grazia, De Palma Clara
Sezione: Istituto Oncologico Europeo
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professor:
Trapani Dario
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Baldassarre Damiano
Sezione: Ospedale di circolo di RHO
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lesson
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professor:
De Angelis Giuseppe
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Bollina Roberto, Molteni Raffaella
Sezione: Ospedale di Crema
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Baldassarre Damiano, Coggi Daniela
Sezione: Ospedale di Magenta
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
Di Toma Luca Francesco, Puricelli Simona Luisa
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Bruni Agnese, Villa Alessandro Maria Giovanni
Sezione: Ospedale Fatebenefratelli
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
Brucato Antonio Luca, Tombetti Enrico
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
De Gennaro Colonna Vito
Sezione: Ospedale Luigi Sacco
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Sezione: Ospedale Maggiore di Lodi
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Sezione: Ospedale Niguarda Ca Granda
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
La Mura Vincenzo, Solbiati Monica
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professors:
Antonucci Flavia, Bissoli Maurizio
Sezione: Ospedale San Carlo
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professor:
Faioni Elena Maria
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Cella Silvano Gabriele
Sezione: Ospedale San Paolo
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018.
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professor:
Faioni Elena Maria
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Lesma Elena Anna
Sezione: Ospedale Uboldo di Cernusco sul Naviglio
Responsible
Prerequisites for admission
Having passed the exams of Anatomy and Human Physiology, General Nursing Sciences, Clinical Nursing Sciences 1 and Internship 1.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
The evaluation of the written barrier test DOES NOT give rise to a mark, but only to admission to the oral test.
The oral exam includes questions the assessment of which relates to the following parameters: content, logic, language properties.
The evaluation of the oral test is out of thirty.
Pharmacology
Course syllabus
1. General pharmacology
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
· What is and what pharmacology deals with
- Concept of drug / toxic
- Discovery and development of new drugs and research phases
- Pharmacovigilance
- Definitions of pharmacodynamics and pharmacokinetics
3. Pharmacodynamics
· Concept of receptor
· Receptor drug interaction: types of bonds
· Effectiveness, Power, Dose-response curve
· Therapeutic index
· Agonist and antagonist drugs
· Competitive and non-competitive, chemical and functional antagonism
· The four superfamilies of receptors: channels, bound to G proteins, enzymatic, intracellular and signal transduction
· Concept of receptor desensitization
4. Pharmacokinetics
· Routes of administration of the drugs.
· Pharmaceutical preparations
· Absorption of drugs
· Distribution of drugs
· Biotransformation of drugs
· Elimination of drugs.
· Main pharmacokinetic parameters.
· Individual variability in drug response
- Placebo effect. Hypersensitivity. Addiction
· Drug interactions and between drugs and foods.
Special Pharmacology
5. Autonomic nervous system
· Sympathetic and parasympathetic system. Adrenergic and cholinergic neurotransmission
· Agonist and antagonist drugs that interfere with adrenergic transmission
· Agonist and antagonist drugs that interfere with cholinergic transmission
6. Other Neurotransmission Systems
· Dopaminergic
· Serotonergic
· Histaminergic
· GABAergic
Drugs used in the pathologies of the different systems and systems
For each system: Main classes of drugs, mechanisms of action, pharmacokinetics, methods of therapeutic use, side / toxic effects
7. Gastrointestinal system
· Drugs used in peptic ulcer therapy
· Prokinetic drugs,
· Anti-emetic and emetic drugs,
· Purgative and antidiarrheal drugs (outline)
8. Drugs used in the treatment of diabetes (insulin and oral hypoglycemic agents)
9. Drugs used to regulate fertility
10. Respiratory System
· Drugs used in the treatment of asthma and allergic rhinitis
· Cough active and mucolytic drugs (outline)
11. Cardiovascular system
· Antihypertensive drugs
· Anti-anginal drugs
· Antiarrhythmic drugs (outline)
· Medicines usable in heart failure
· Medicines for blood diseases
12. Musculoskeletal system
· Nonsteroidal anti-inflammatory drugs
· Glucocorticoids.
Central nervous system drugs
13. Central analgesic drugs
2. Anxiolytic - hypnotic drugs
3. Antidepressant medications
4. Pain therapy
5. Drugs used in Parkinson's disease
6. Drugs used in Alzheimer's disease
7. Antipsychotic drugs
8. Antiepileptic drugs
20. Antimicrobial chemotherapy
· Main classes of antibacterial drugs and their clinical use
· Drugs active against the main protozoa, fungi, viruses
9. General principles of anticancer chemotherapy and main classes of drugs
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
Course syllabus
1. Introduction to clinical medicine
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
· The practice of Medicine
· Decision-making in Clinical Medicine
2. Chest pain
· Of cardiac origin
- Coronary syndrome
- Pericarditis
· Of respiratory origin
- Pulmonary thromboembolism
- Pneumothorax
- Pleural effusions
· Of other origin
- Oesophagitis
3. Blood pressure changes
· Hypertension - hypotension
· Lipotimia, syncope
· Cardiogenic shock
4. Changes in heart rhythm
· Bradyarrhythmias
· Tachyarrhythmias
5. Impairment of the function of the respiratory system
· Dyspnoea of cardiac origin
- Heart failure
- Acute pulmonary edema
- Cardiac asthma
· Dyspnoea of respiratory origin
- Asthma
- COPD
- Respiratory failure
6. Alterations in the function of the gastrointestinal tract
· Dysphagia, nausea, vomiting
· Diarrhea, constipation
· Gastrointestinal bleeding, hematemesis, melena
· Ascites
· Jaundice
· Cirrhosis
7. Abdominal pain
· Gastritis, ulcer
· Inflammatory bowel disease
· Diverticulitis, diverticulosis
· Irritable colon
8. Alterations of the hematological function
· Anemia
· Poliglobulie
· Coagulation, bleeding disorders
· Transfusions
9. Changes in kidney and urinary function
· Polyuria, oliguria, anuria
· Hematuria, proteinuria, bacteriuria
· Acute, chronic renal failure
· Edema
· Nephritic syndrome
· Nephrotic syndrome
10. Endocrine-metabolic alterations
· Diabetes
· Hyper - hypo thyroidism
11. Changes in body temperature
· Fever, hyperthermia
· Fevers of unknown origin
· Hypothermia, frostbite
12. Infections
· General information on infections
· The immunocompromised patient
· Of the cardiovascular system
- Endocarditis
· Respiratory system
- Pneumonia
- Tuberculosis
· Of the gastrointestinal system
- Salmonellosis
- Notes on food poisoning
- Hepatitis
· Of the renal system
- Pyelonephritis
- Urinary tract infections
13. Oncology
· Main malignancies
- Respiratory system
- Of the gastrointestinal system
- Of the renal system
- Of the hematological system
Teaching methods
Frontal lessons
Teaching Resources
Antonelli Incalzi R. et al. Medicina Interna per Scienze Infermieristiche. Padova:Piccin; 2012
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Massini R, Izzi D, Marchetti P. Medicina interna. (6ed) Mialno: McGraw Hill 2019.
Rugarli C, et al. Medicina Interna Sistematica. Milano: Edra, 2015.
Kasper DL, Fauci AS, Longo DL, Loscalzo J, Jameson JL. Harrison. Principi di Medicina interna
(20ed). Milano: Casa Editrice ambrosiana, 2021. vol 1 e 2.
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana). Bologna: Zanichelli editore; 2020.
Di Giulio AM, Cella SG, Gorio A, Scaglione F, Carelli S. Farmacologia generale e Speciale. Per le lauree sanitarie. (2ed). Padova: Piccin 2018
Govoni S. Farmacologia. Milano: Casa Editrice Ambrosiana; 2014.
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
D'Angelo Francesco, De Monte Andrea
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Professor:
Nisoli Enzo
Sezione: San Giuseppe
Responsible
Internal medicine
MED/09 - INTERNAL MEDICINE - University credits: 4
Lessons: 60 hours
Professors:
Froldi Marco, Harari Sergio Alfonso
Pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 60 hours
Educational website(s)
Farmacologia - Mod.
Farmacologia - Mod. - Rho
Farmacologia - modulo (a.a. 2023/24)
Medicina e farmacologia - Cernusco (a.a. 2023/24)
Medicina e farmacologia - Istituto Tumori (a.a. 2023/24)
Medicina e farmacologia - Lodi (a.a. 2023/24)
Medicina e farmacologia – Magenta
Medicina e farmacologia - Niguarda
Medicina e farmacologia - San Giuseppe
Medicina e farmacologia - San Paolo (a.a. 2023/24)
Farmacologia - Mod. - Rho
Farmacologia - modulo (a.a. 2023/24)
Medicina e farmacologia - Cernusco (a.a. 2023/24)
Medicina e farmacologia - Istituto Tumori (a.a. 2023/24)
Medicina e farmacologia - Lodi (a.a. 2023/24)
Medicina e farmacologia – Magenta
Medicina e farmacologia - Niguarda
Medicina e farmacologia - San Giuseppe
Medicina e farmacologia - San Paolo (a.a. 2023/24)
Professor(s)
Reception:
from 2pm to 4pm tuesday, wednesday, thursday
At the Oncology Department - Rho Hospital - corso Europa 250
Reception:
Dept. Biomedical and Clinical Science-H Sacco
Reception:
Friday 10:00-12:30 a.m.
Department of Health Sciences, Via Antonio di Rudinì 8
Reception:
on appointment to be organised via e-mail
"Palazzina LITA-Vialba"
Reception:
to be scheduled by email
Via Francesco Sforza 35, Milan
Reception:
On Thursdays, at 3 p.m.
CET, via Pace 9 Milano, Pad 2, first floor
Reception:
On appointment (send an email)
Exercise Medicine Units, IRCCS Istituto Auxologico Italiano, via Pier Lombardo 22
Reception:
meeting appointment to be scheduled by email
ex-Department of Medical Pharmacology, via L. Vanvitelli 32 - 20129 Milan - New Building, Third Floor