Pathogenesis and diagnostics

A.Y. 2019/2020
6
Max ECTS
90
Overall hours
SSD
BIO/12 MED/04 MED/07 MED/36
Language
Italian
Learning objectives
To know the structure of the main pathogenic microorganisms for humans
To know the physiological defense mechanisms of the organism
To know the relationship between pathogenic and host microorganisms in human infections
To know the methods and use of radiation
To know the methods of laboratory diagnostics
To know the laboratory tests and the imaging diagnostic tests typical of pathological pictures
To know the reference parameters of laboratory diagnostics and diagnostic imaging
To know the current radiation protection standards
To know the causes, the pathogenetic and pathophysiological mechanisms of diseases
To describe the main cellular changes during illness
To know the inflammatory and healing processes
Expected learning outcomes
The student will describe the EU radiation protection standards.
It will link pathogenic microorganisms with the physiological defense mechanisms in human infections.
It will recognize signs and symptoms of inflammatory diseases.
It will identify the causes and physiopathogenetic mechanisms underlying the diseases
The student will illustrate the specific diagnostic investigations for the different pathological conditions.
It will interpret the results of diagnostic investigations in relation to the reference parameters.
Course syllabus and organization

Sezione: Busto Arsizio

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Braga Federica
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Marvaso Giulia
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Baroli Alberto

Sezione: Cernusco

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Capitanio Daniele
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Secchi Francesco
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Bianchi Emanuela
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Mascherpa Mauro

Sezione: Crema

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Paroni Rita Clara
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Valdameri Paolo
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Bonetti Cristina
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Inzoli Alessandro

Sezione: Don Gnocchi

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Paroni Rita Clara
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Secchi Francesco
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professors: Casati Lavinia, Fenizia Claudio, Gnocchi Pierluigi Carlo

Sezione: Fatebenefratelli

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Goi Giancarlo
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Mariani Davide
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Grande Romualdo
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Recalcati Stefania

Sezione: IEO

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Goi Giancarlo
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Bellomi Massimo
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Morace Giulia
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Costanzo Vincenzo

Sezione: Magenta

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Goi Giancarlo
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Gammella Elena

Sezione: Niguarda

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Paroni Rita Clara
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Vanzulli Angelo
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professors: Bielli Alessandra, Perno Carlo Federico
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours

Sezione: Policlinico

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Paroni Rita Clara
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Mattina Roberto
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours

Sezione: Rho

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Braga Federica
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Mauri Carla
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Giuliani Giuseppe
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Basilico Nicoletta

Sezione: Sacco

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
ntroduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Braga Federica
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Mariotti Massimo

Sezione: San Carlo

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Goi Giancarlo
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Zoffoli Elena
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours

Sezione: San Donato

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Braga Federica
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Secchi Francesco
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Gaia Paola
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Pastorelli Luca

Sezione: San Giuseppe

Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Bestetti Alberto
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Deflorio Loredana
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Basilico Nicoletta

Sezione: San Paolo

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Barassi Alessandra
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Mauri Giovanni
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Borghi Elisa
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Scita Giorgio

Sezione: Tumori

Responsible
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochimica clinica e biologia molecolare clinica
Course syllabus
Clinical biochemistry: introductions, purposes and definitions
Laboratory tests
Blood and urine sample
Other types of biological sample
Concept of total variability; biological variability and influencing factors
Patient preparation
Pre-analytical variability: sampling, storage, transport and delivery
Acceptance criteria for biological sample
Analytical variability
Types of errors. Reliability of dosage method
Quality checks
Post-analytical variability: reporting
Reference values
Analytical goals and critical difference
Logic diagnostic: clinical sensitivity and specificity, predictive values
Deepening of some topics chosen by the teacher (the role of the laboratory in situations like heart attack, diabetes, liver disease, dyslipidemia )
Teaching methods
Frontal lessons
Teaching Resources
Allan Gaw, Michael J. Murphy et al. Biochimica clinica. (3ed). Milano: Elsevier MASSON 2007
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Federici G. Medicina di laboratorio. Milano: McGraw Hill, 2014
Patologia generale
Course syllabus
Introduction of epigenetica
Disease concept: aetiology and pathogenesis
Cell pathology (necrosis and apoptosis)
Storage Disease (steatosis and amyloidosis)
Humoral and cellular immunology and immunopathology
Acute inflammation (margining and chemotaxis, phagocytosis, mediators of inflammation, systemic reactions)
Chronic inflammation
Wound healing
Pathogenetic and physiopathological causes and mechanisms of diseases: Diabetes, Anemias and red blood cell pathology, Pathology of blood coagulation
Atherosclerosis
Benign and malignant tumors, oncogenes and tumor suppressor genes, metastasis
Teaching methods
Frontal lessons
Teaching Resources
Pontieri GM. Elementi di Patologia generale e fisiopatologia generale. Per i corsi di laurea in professioni sanitarie. (4ed). Milano: Piccin, 2018
Microbiologia e microbiologia clinica
Course syllabus
The main differences of the cells of prokaryotic and eukaryotic microorganisms about the structure, organization and methods of reproduction. Differences between microorganisms and viruses
Horizontal and vertical transmission of microorganism, viruses, and the importance of vehicles and carriers - main pathogenicity and virulence characteristics of microorganisms
Host-pathogen interaction: colonization, symbiosis, commensalism, infection and disease - factors facilitating microbial invasion
Sterilization and disinfection procedures - mechanism of action of disinfectants and main applications
Criteria for the collection and transport of biological samples for microbiological diagnosis in the laboratory - direct and indirect diagnosis of infection
Main direct and indirect microbiological investigations - diagnostic investigations in relation to the infection phase (recent, regressed and chronic infection) and to the therapeutic orientation (sensitivity tests for antimicrobial drugs)
Ultrastructure and functions of the different components of the bacterial cell, chemical composition and structure of the cell wall of gram positive and gram negative bacteria, reproduction.
Mechanism of action of antibacterial inhibitor drugs of cell wall synthesis, cytoplasmic membrane functions, protein and nucleic acid synthesis and microbial drug-resistance mechanisms
Morphology, ultrastructure and function of the components of the fungal cell, sexual and asexual reproduction - main antifungal drugs, mechanism of action and possible development of resistance
Morphology, relationship between structures and functions, and mode of reproduction of protozoa
Origin, organization and methods of replication of animal viruses - persistent, slow, latent viral infection - main antiviral drugs and mechanisms of action
Resident microbiota of the human body and composition in the various apparatuses
Characteristics of: Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus spp, pathogenic neisseria, enterobacteria, sporigenic bacilli, mycobacterium
Morphological, cultural and pathogenic characteristics of the main fungal agents with particular reference to Candida, Cryptococcus and Aspergillus
Notes on the main protozoa of human interest
The main agents of viral infections (Herpesviridae, Orthomyxoviridae, Paramyxoviridae, Picornaviridae retroviridae and hepatic viruses)
Nosocomial infections: definition, risk factors and main pathogens
Teaching methods
Frontal lessons
Teaching Resources
Eudes Lanciotti. Elementi di microbiologia clinica. Milano: Casa editrice Ambrosiana, 2017
Diagnostica per immagini e radioterapia
Course syllabus
Basics of physics, principles of radiobiology
Radiation protection for operators
Diagnostic radiology: therapeutic indications and contraindications; radiation protection for patients
Nuclear medicine: therapeutic indications and contraindications; radiation protection for patients
Radiotherapy: therapeutic indications and contraindications; radiation protection for patients
Teaching methods
Frontal lessons
Teaching Resources
Cittadini, Cittadini, Sardanelli. Diagnostica per immagini e radioterapia. Milano: EDRA 2015
Biochimica clinica e biologia molecolare clinica
BIO/12 - CLINICAL BIOCHEMISTRY AND MOLECULAR BIOLOGY - University credits: 1
E-learning: 15 hours
Professor: Paleari Renata
Diagnostica per immagini e radioterapia
MED/36 - IMAGING AND RADIOTHERAPY - University credits: 1
Lessons: 15 hours
Professor: Mauri Giovanni
Microbiologia e microbiologia clinica
MED/07 - MICROBIOLOGY AND CLINICAL MICROBIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Sisto Francesca
Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 30 hours
Professor: Recalcati Stefania