Systems and Diseases Ii

A.Y. 2023/2024
21
Max ECTS
268
Overall hours
SSD
MED/03 MED/08 MED/09 MED/12 MED/13 MED/15 MED/16 MED/18
Language
Italian
Learning objectives
The course represents the synthesis of the notions acquired during the first 3 years and the basis for the subsequent detailed clinical studies the will be carried out during Medical and Specialized Clinics.
The objects are the following:
-to provide the student with the knowledge on the main diseases of Gastrointestinal, Endocrinological, Emathological and Immunoreumathological systems (in particular, etiology, pathophysiology and clinical manifestations)
-to give the main information on the genetics and pathological basis of the above-mentioned diseases
-to provide students with the preparatory tools (language, case history, medical examination) for a correct approach to the patient
-to provide with the main clinical, biochemical, instrumental investigations available to perform a correct diagnosis
Expected learning outcomes
1)To know the pathophysiology of:
DIGESTIVE TRACT
Dysphagia, Dyspepsia, gastroesophageal reflux, chronic gastritis, ulcer
Abdominal distension, Gas, digestion problems, Malabsorption
Intestinale obstruction
Abdominal pain
Jaundice
Hepatic insufficiency, viral and toxic hepatitis, liver diseases such as hemochromatosis and Wilson disease, sclerosant cholangitis
Hepatic encephalopathy
Portal hypertension
Biliary lithiasis
Ascites
Constipation
Diarrhea
Gastrointestinal bleeding
Chronic inflammatory bowel diseases (Crohn disease and ulcerative rectocolitis).

ENDOCRINE - METABOLIC SYSTEM:
Feed-back mechanism and interaction with the other systems
Circadian rithms of hormone secretion. Hormones mechanisms of action
Pathogenetic mechanisms of endocrine disorders and of metabolic diseases: eccess and deficiency
Hormone resistance, bioactivity, alterations of hormone peripheral metabolism
Diseases of thyroid, parathyroids, adrenals, gonads, hypothalamus and pituirary
Metabolic syndrome, insulin resistance
Diabetes type 1&2, gestational diabetes, obesity, hyperuricemia
Monogenic diabetes and obesity
Diabetes complications
Bone metabolism and osteoporosis
Hormones and nutrition

BLOOD:
Differentiation and maturation of blood cells
Role of growth factors
Pathophysiology of the main diseases of blood and lymphohemopoietic organs
Lymphoproliferative and Mieloproliferative diseases
Polycythemia vera and secondary polycythemia
Essential thrombocythemia

IMMUNE SYSTEM:
1) Approach to immunodeficiencies
Approach to autoimmune diseases
Approach to allergic diseases, asthma, rhinitis
Inflammatory arthritis
Infectious and post-infectious arthritis
Microcrystalline arthritis
Diseases of the connective tissue
Systemic vasculitis
Bone diseases
Painful syndromes
2) To know how to define a disease, its epidemiology, etiology and pathophysiology, nosography, signs and symptoms; to interpret the pathophysiological causes of signs and symptoms, the biochemical data, the instrumental investigations. The genetics and pathological basis is also requested for certain diseases.

3) To know the indications and limitations of the main diagnostic approaches
Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Course syllabus and organization

Linea: Policlinico

Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Shifts:
Turno
Professors: Corradini Paolo, Onida Francesco
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Shifts:
Gruppo 1
Professor: Mantovani Giovanna
Gruppo 2
Professor: Mantovani Giovanna
Gruppo 3
Professors: Arosio Maura, Muller Ilaria
Gruppo 4
Professor: Giavoli Claudia
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours
Shifts:
Turno
Professors: Boni Luigi, Dionigi Gianlorenzo
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours
Professor: Bellocchi Chiara
Shifts:
Turno
Professor: Bellocchi Chiara
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
Lessons: 24 hours
Professor: Ghezzi Daniele
Shifts:
Turno
Professor: Ghezzi Daniele
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours
Shifts:
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 24 hours

Linea: San Donato

Responsible
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professors: Finazzi Maria Chiara, Lussana Federico, Rambaldi Alessandro
Shifts:
Turno
Professors: Finazzi Maria Chiara, Lussana Federico, Rambaldi Alessandro
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professor: Vecchi Maurizio
Shifts:
Turno
Professor: Vecchi Maurizio
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours
Shifts:
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours
Professor: Zanichelli Andrea
Shifts:
Turno
Professor: Zanichelli Andrea
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
Lessons: 24 hours
Professor: Alcalay Myriam
Shifts:
Turno
Professor: Alcalay Myriam
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours
Professor: Pruneri Giancarlo
Shifts:
Turno
Professor: Pruneri Giancarlo
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 24 hours
Shifts:

Linea: San Giuseppe

Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 36 hours
Professors: Cerini Federica, Lampertico Pietro, Rumi Mariagrazia, Vecchi Maurizio
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 12 hours
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 12 hours
Professor: Bellocchi Chiara
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
Lessons: 24 hours
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 24 hours
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 24 hours
Professor(s)
Reception:
by appointment via email
Fondazione IRCCS Ospedale Maggiore Policlinico, building ZONDA , via Lamarmora 5
Reception:
by appointment arranged by e-mail
Padiglione Zonda - Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - second floor
Reception:
Scala C III piano stanza 13
Reception:
Thursday 12.00 am - 01.00 pm
IRCCS Istituto Auxologico, via Ariosto 9, Milan
Reception:
Wednesday, 16.00-18.00 (only by appointment to be made by email)
ASST Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milano
Reception:
by telephone appointment
via L. Temolo 4, 20126 Milano - Lab of Neurogenetics and mitochondrial disorders
Reception:
To be arranged by e-mail
Hematology, Fatebenefratelli Hospital, Via Castelfidardo n.15, 20121 Milano
Reception:
Monday 12.00-13.00 (by appointment)
Interhospital Pathology Division, Science and Technology Park, Via Fantoli 16/15, 20138 Milano